313552-29-3
313552-29-3
Chemical Structure
BMS-684
- CAS No.: 313552-29-3
- Formula:C27H26N4O3
- Molecular Weight:454.52
InChIKey: XIVOLEKHEMYRBO-UHFFFAOYSA-N
SMILES: CN(C1=CC=CC=C1C(N2CCN(C(C3=CC=CC=C3)C4=CC=CC=C4)CC2)=C5[N+]([O-])=O)C5=O
Biological Activity: BMS-684 is a selective DGKα inhibitor with an IC50 of 15 nM. BMS-684 inhibits DGKα kinase activity with >100-fold selectivity over the related DGK type I family members DGKβ and DGKγ. BMS-684 does not inhibit any of the other seven DGK isozymes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BMS-684 | 98.52% | BMS-684 is a selective DGKα inhibitor with an IC50 of 15 nM. BMS-684 inhibits DGKα kinase activity with >100-fold selectivity over the related DGK type I family members DGKβ and DGKγ. BMS-684 does not inhibit any of the other seven DGK isozymes. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.62
HY-149666BMS-496 -
Similarity Score 0.61
HY-149874BMS-502 -
Similarity Score 0.59
HY-123205Oxatomide -
Similarity Score 0.57
HY-W754020Elbanizine -
Similarity Score 0.54
HY-117162S 1432 -
Similarity Score 0.54
HY-106306Laprafylline -
Similarity Score 0.53
HY-123229Ropizine -
Similarity Score 0.52
HY-B1090RCinnarizine (Standard) -
Similarity Score 0.52
HY-161643S21-1011 -
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