BMS-496
Based on 1 Customer Validation
BMS-496 is adualDGKα/ζlipid kinase inhibitor, with theIC50of 0.09 (DGKα) and 0.006 μM (DGKζ).
For research use only. We do not sell to patients.
- Purity: 99.72%
- CAS No.: 2407854-31-1
- Formula: C26H22BrF2N5O3
- Molecular Weight:570.39
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
0.09, 0.006 μM (DGKα,DGKζ)[1].
Chemical Information
-
CAS No. 2407854-31-1
-
Appearance Solid
-
Molecular Weight 570.39
-
Formula C26H22BrF2N5O3
-
Color Light yellow to yellow
-
SMILES
CN(C1=CC=C(Br)N=C1C(N2CCN(C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2)=C5[N+]([O-])=O)C5=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (175.32 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7532 mL | 8.7659 mL | 17.5319 mL | 43.8297 mL |
| 5 mM | 0.3506 mL | 1.7532 mL | 3.5064 mL | 8.7659 mL | |
| 10 mM | 0.1753 mL | 0.8766 mL | 1.7532 mL | 4.3830 mL | |
| 15 mM | 0.1169 mL | 0.5844 mL | 1.1688 mL | 2.9220 mL | |
| 20 mM | 0.0877 mL | 0.4383 mL | 0.8766 mL | 2.1915 mL | |
| 25 mM | 0.0701 mL | 0.3506 mL | 0.7013 mL | 1.7532 mL | |
| 30 mM | 0.0584 mL | 0.2922 mL | 0.5844 mL | 1.4610 mL | |
| 40 mM | 0.0438 mL | 0.2191 mL | 0.4383 mL | 1.0957 mL | |
| 50 mM | 0.0351 mL | 0.1753 mL | 0.3506 mL | 0.8766 mL | |
| 60 mM | 0.0292 mL | 0.1461 mL | 0.2922 mL | 0.7305 mL | |
| 80 mM | 0.0219 mL | 0.1096 mL | 0.2191 mL | 0.5479 mL | |
| 100 mM | 0.0175 mL | 0.0877 mL | 0.1753 mL | 0.4383 mL |