314-03-4
Chemical Structure
Pimethixene
Synonym(s): Pimetixene
- CAS. Nr.: 314-03-4
- Formula:C19H19NS
- Molecular Weight:293.43
IUPAC Name: 1-methyl-4-(9H-thioxanthen-9-ylidene)piperidine
InChIKey: NZLVRVYNQYGMAB-UHFFFAOYSA-N
SMILES: CN1CC/C(CC1)=C2C3=C(SC4=C\2C=CC=C4)C=CC=C3
Biological Activity: Pimethixene is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors, with pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Pimethixene | Pimethixene is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors, with pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
