338404-52-7
338404-52-7
Chemical Structure
CITCO
- CAS No.: 338404-52-7
- Formula:C19H12Cl3N3OS
- Molecular Weight:436.74
IUPAC Name: (E)-6-(4-chlorophenyl)imidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime
InChIKey: ZQWBOKJVVYNKTL-AUEPDCJTSA-N
SMILES: ClC1=CC=C(C2=C(/C=N/OCC3=CC=C(Cl)C(Cl)=C3)N4C(SC=C4)=N2)C=C1
Biological Activity: CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CITCO | 99.60% | CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. | ||||||||||||||||||||
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CITCO (Standard) | ≥98% | CITCO (Standard) is the analytical standard of CITCO (HY-103244). This product is intended for research and analytical applications. CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. | ||||||||||||||||||||
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