37686-84-3
37686-84-3
Chemical Structure
TDHL
Synonym(s): Tergurid; Terguride; trans-Dihydrolisuride
- CAS 番号: 37686-84-3
- Formula:C20H28N4O
- Molecular Weight:340.46
IUPAC Name: 1,1-diethyl-3-((6aR,9S,10aR)-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolin-9-yl)urea
InChIKey: JOAHPSVPXZTVEP-YXJHDRRASA-N
SMILES: CN1[C@@]2([H])[C@@](C[C@@H](C1)NC(N(CC)CC)=O)([H])C3=CC=CC4=C3C(C2)=CN4
Biological Activity: TDHL (Tergurid) is a dopamine receptor agonist with a Kd of 0.39 nM for D2 receptor and an orally available 5-HT-2 receptor antagonist.
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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TDHL | 99.9% | TDHL (Tergurid) is a dopamine receptor agonist with a Kd of 0.39 nM for D2 receptor and an orally available 5-HT-2 receptor antagonist. | ||||||||||||||||||||
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TDHL-d10 | TDHL-d10 (Tergurid-d10; Terguride-d10; trans-Dihydrolisuride-d10) is the deuterium labeled TDHL (HY-12714). TDHL (Tergurid) is a dopamine receptor agonist with a Kd of 0.39 nM for D2 receptor and an orally available 5-HT-2 receptor antagonist. | |||||||||||||||||||||
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Proterguride | Proterguride is a potent dopamine receptor agonist. Proterguride also shows antagonistic properties at the histamine H(1) receptor and alpha(1)-adrenoceptor and partially agonize serotonergic 5-HT2A/B receptor. Proterguride can be used for the research of neurological disease, such as Parkinson's disease . | |||||||||||||||||||||
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Cianergoline | Cianergoline is a ergoline derivative with the activity of reducing intraocular pressure (IOP). Its primary regulatory mechanism involves the inhibition of sympathetic nervous function, achieved through actions on both prejunctional (DA2) and postjunctional (α1) adrenergic receptors. Cianergoline can be used for research in the field of glaucoma. | |||||||||||||||||||||
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CQP-201403 | CQP-201403 is a dopamine receptor agonist. CQP-201403 can be used for the research of neurological disease. | |||||||||||||||||||||
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LY 116467 | LY 116467 is an active compound. | |||||||||||||||||||||
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Disulergine | Disulergine (CH 29-717) is an ergot alkaloid. Disulergine is a dopamine receptor agonist. Disulergine inhibits secretion of prolactin in rats. Disulergine inhibits growth hormone (GH) release. | |||||||||||||||||||||
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LY86057 | LY86057 is an ergoline derivative without N1 substituents. It has higher affinity for porcine, squirrel monkey and human 5-HT2 receptors than rats and is an antagonist of 5-HT2 receptors. When studying the differences in recognition of a series of ergolines between species, LY86057 was found to be more selective for 5-HT2 receptors. Compared with LY53857, LY108742 resulted in a higher affinity for rat 5-HT2 receptors even when the N1 substituent was only methyl. | |||||||||||||||||||||
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Pergolide | 99.68% | Pergolide (LY127809 free base), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptor agonist. Pergolide can be used for Parkinson's disease and hyperprolactinaemia research. | ||||||||||||||||||||
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Pergolide sulfone | Pergolide sulfone is a Pergolide metabolite. | |||||||||||||||||||||
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SDZ 208-912 | SDZ 208-912 is a dual-action 5-HT1A/2 receptor agonist and dopamine D1 receptor antagonist. SDZ 208-912 exhibits partial dopamine agonism and atypical neurosedative effects in rodent models. SDZ 208-912 can be used in research on neurological disorders such as schizophrenia. | |||||||||||||||||||||
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Dihydrolysergic acid | 99.89% | Dihydrolysergic acid is a fungal ergot alkaloid and also the dihydro analog of lysergic acid. Dihydrolysergic acid serves as a precursor for vasodilatory ergot alkaloid-derived drugs. Dihydrolysergic acid can be biosynthesized by expressing intron-free synthetic Claviceps africana cloA in an Neosartorya fumigata easM knockout strain. | ||||||||||||||||||||
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