2. Metabolic Enzyme/Protease Others
  3. Endogenous Metabolite Drug Intermediate
  4. Dihydrolysergic acid

Dihydrolysergic acid is a fungal ergot alkaloid and also the dihydro analog of lysergic acid. Dihydrolysergic acid serves as a precursor for vasodilatory ergot alkaloid-derived drugs. Dihydrolysergic acid can be biosynthesized by expressing intron-free synthetic Claviceps africana cloA in an Neosartorya fumigata easM knockout strain.

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Dihydrolysergic acid

Dihydrolysergic acid Chemical Structure

CAS No. : 5878-43-3

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Dihydrolysergic acid Related Antibodies

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Description

Dihydrolysergic acid is a fungal ergot alkaloid and also the dihydro analog of lysergic acid. Dihydrolysergic acid serves as a precursor for vasodilatory ergot alkaloid-derived drugs. Dihydrolysergic acid can be biosynthesized by expressing intron-free synthetic Claviceps africana cloA in an Neosartorya fumigata easM knockout strain[1][2].

In Vitro

Dihydrolysergic acid (compound 1) is prepared via alkaline catalytic hydrolysis of Methyl (6aR,9R,10aR)-7-Methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxylate (compound 18)[1].
Dihydrolysergic acid (DHLA) is biosynthesized when intron-free synthetic Claviceps africana cloA is expressed in festuclavine-accumulating Neosartorya fumigata easM knockout strains[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Dihydrolysergic acid Related Antibodies
Molecular Weight

270.33

Formula

C16H18N2O2
CAS No.
SMILES

CN1[C@@]2([H])[C@@](C[C@H](C1)C(O)=O)([H])C3=CC=CC4=C3C(C2)=CN4
Structure Classification
Initial Source

Claviceps gigantea
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Dihydrolysergic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dihydrolysergic acid5878-43-3Endogenous MetaboliteDrug IntermediateDrug Iintermediatelysergic acidHPLCNeosartorya fumigataergot alkaloidClaviceps africanaeasM knockout straincloAfestuclavineLC-MSInhibitorinhibitorinhibit

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Dihydrolysergic acid
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