388627-21-2
388627-21-2
Chemical Structure
GW297361
- CAS No.: 388627-21-2
- Formula:C16H12N4O3S2
- Molecular Weight:372.42
IUPAC Name: (Z)-4-(((7-oxo-6,7-dihydro-8H-thiazolo[5,4-e]indol-8-ylidene)methyl)amino)benzenesulfonamide
InChIKey: LTYGAJVXAFJKSY-XFFZJAGNSA-N
SMILES: O=S(C1=CC=C(N/C=C(C2=C(SC=N3)C3=CC=C2N4)\C4=O)C=C1)(N)=O
Biological Activity: GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GW297361 | 98.05% | GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Structural Analogs
-
Similarity Score 0.77
HY-112358GW8510 -
Similarity Score 0.62
HY-112471TrkA Inhibitor -
Similarity Score 0.59
HY-13977APKR-IN-C16 -
Similarity Score 0.53
HY-112460CDK2-IN-3 -
Similarity Score 0.51
HY-112386OXSI-2 -
Similarity Score 0.49
HY-146010Carbonic anhydrase inhibitor 13 -
Similarity Score 0.48
HY-101464ML329 -
Similarity Score 0.47
HY-111931Indirubin-3'-monoxime-5-sulphonic acid -
Similarity Score 0.47
HY-111932Indirubin-5-sulfonate -
Explore the MedChemAI to find more analogs
