39628-94-9
Chemical Structure
p-Nitrobenzyl mesylate
Synonym(s): 4-Nitrobenzyl mesylate; para-Nitrobenzyl mesylate; PNBM
- CAS No.: 39628-94-9
- Formula:C8H9NO5S
- Molecular Weight:231.23
IUPAC Name: 4-nitrobenzyl methanesulfonate
InChIKey: QZIYKAFPHRTIAI-UHFFFAOYSA-N
SMILES: CS(OCC1=CC=C(C=C1)[N+]([O-])=O)(=O)=O
Biological Activity: p-Nitrobenzyl mesylate (4-Nitrobenzyl mesylate) is an alkylating reagent. p-Nitrobenzyl mesylate alkylates thiophosphorylated serine, threonine, tyrosine residues and cysteine thiols, without modifying hydroxyl, amino or carboxylic acid functional groups. p-Nitrobenzyl mesylate generates thiophosphate epitopes on thiophosphorylated substrate proteins for recognition by thiophosphate-specific antibodies. p-Nitrobenzyl mesylate facilitates the identification and purification of kinase substrates. p-Nitrobenzyl mesylate is applicable to studies related to cerebral ischemia-reperfusion injury[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
p-Nitrobenzyl mesylate | 98.78% | p-Nitrobenzyl mesylate (4-Nitrobenzyl mesylate) is an alkylating reagent. p-Nitrobenzyl mesylate alkylates thiophosphorylated serine, threonine, tyrosine residues and cysteine thiols, without modifying hydroxyl, amino or carboxylic acid functional groups. p-Nitrobenzyl mesylate generates thiophosphate epitopes on thiophosphorylated substrate proteins for recognition by thiophosphate-specific antibodies. p-Nitrobenzyl mesylate facilitates the identification and purification of kinase substrates. p-Nitrobenzyl mesylate is applicable to studies related to cerebral ischemia-reperfusion injury. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.80
HY-W012469O-(4-Nitrobenzyl)hydroxylamine hydrochloride -
Similarity Score 0.79
HY-W009454Potassium p-nitrophenyl sulfate -
Similarity Score 0.77
HY-41464Ethyl 4-nitrobenzoate -
Similarity Score 0.77
HY-W0155704-Nitrobenzyl alcohol -
Similarity Score 0.76
HY-34158N-(4-Nitrophenethyl)acetamide -
Similarity Score 0.75
HY-Y01854'-Nitroacetophenone -
Similarity Score 0.74
HY-W0075774-Nitrobenzaldehyde -
Similarity Score 0.74
HY-138342Benzyl-PEG1-MS -
Similarity Score 0.74
HY-W014405H-DL-Phe(4-NO2)-OH -
Explore the MedChemAI to find more analogs
References
- [1]. Allen JJ, et al. A semisynthetic epitope for kinase substrates. Nat Methods. 2007 Jun;4(6):511-6. [Content Brief]
- [2]. Kumar V, et al. Generation and characterization of ATP analog-specific protein kinase Cδ. J Biol Chem. 2015;290(4):1936-1951. [Content Brief]
- [3]. Leissing F, et al. Substrate thiophosphorylation by Arabidopsis mitogen-activated protein kinases. BMC Plant Biol. 2016;16:48. Published 2016 Feb 24. [Content Brief]
