40662-45-1
Chemical Structure
2-Hydroxyisobutyric acid-d6
- CAS No.: 40662-45-1
- Formula:C4H2D6O3
- Molecular Weight:110.14
IUPAC Name: 2-hydroxy-2-(methyl-d3)propanoic-3,3,3-d3 acid
InChIKey: BWLBGMIXKSTLSX-WFGJKAKNSA-N
SMILES: [2H]C([2H])([2H])C(C([2H])([2H])[2H])(O)C(O)=O
Biological Activity: 2-Hydroxyisobutyric acid-d6 is the deuterated-labeled 2-Hydroxyisobutyric acid (HY-W015924). 2-Hydroxyisobutyric acid (2-HIBA) is a selective modulator of the Insulin/IGF-1 pathway and the p38 MAPK pathway, which reduces reactive oxygen species (ROS) and fat accumulation in Caenorhabditis elegans. 2-Hydroxyisobutyric acid promotes β-oxidation and inhibits fatty acid synthesis by upregulating SKN-1/NRF2 and downregulating SREBP-1c transcription factors. 2-Hydroxyisobutyric acid has anti-aging and lipid-lowering effects, and can be used to study metabolic diseases such as obesity and diabetes. 2-Hydroxyisobutyric acid is also a renewable precursor of methacrylate through 2-HIB-CoA mutase-mediated biosynthesis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
2-Hydroxyisobutyric acid-d6 | 98.70% | 2-Hydroxyisobutyric acid-d6 is the deuterated-labeled 2-Hydroxyisobutyric acid (HY-W015924). 2-Hydroxyisobutyric acid (2-HIBA) is a selective modulator of the Insulin/IGF-1 pathway and the p38 MAPK pathway, which reduces reactive oxygen species (ROS) and fat accumulation in Caenorhabditis elegans. 2-Hydroxyisobutyric acid promotes β-oxidation and inhibits fatty acid synthesis by upregulating SKN-1/NRF2 and downregulating SREBP-1c transcription factors. 2-Hydroxyisobutyric acid has anti-aging and lipid-lowering effects, and can be used to study metabolic diseases such as obesity and diabetes. 2-Hydroxyisobutyric acid is also a renewable precursor of methacrylate through 2-HIB-CoA mutase-mediated biosynthesis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
2-Hydroxyisobutyric acid (Standard) | 99.15% | 2-Hydroxyisobutyric acid (Standard) is the analytical standard of 2-Hydroxyisobutyric acid. This product is intended for research and analytical applications. 2-Hydroxyisobutyric acid (2-HIBA) is a selective modulator of the Insulin/IGF-1 pathway and the p38 MAPK pathway, which reduces reactive oxygen species (ROS) and fat accumulation in Caenorhabditis elegans. 2-Hydroxyisobutyric acid promotes β-oxidation and inhibits fatty acid synthesis by upregulating SKN-1/NRF2 and downregulating SREBP-1c transcription factors. 2-Hydroxyisobutyric acid has anti-aging and lipid-lowering effects, and can be used to study metabolic diseases such as obesity and diabetes. 2-Hydroxyisobutyric acid is also a renewable precursor of methacrylate through 2-HIB-CoA mutase-mediated biosynthesis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
2-Hydroxyisobutyric acid | 98.0% | 2-Hydroxyisobutyric acid (2-HIBA) is a selective modulator of the Insulin/IGF-1 pathway and the p38 MAPK pathway, which reduces reactive oxygen species (ROS) and fat accumulation in Caenorhabditis elegans. 2-Hydroxyisobutyric acid promotes β-oxidation and inhibits fatty acid synthesis by upregulating SKN-1/NRF2 and downregulating SREBP-1c transcription factors. 2-Hydroxyisobutyric acid has anti-aging and lipid-lowering effects, and can be used to study metabolic diseases such as obesity and diabetes. 2-Hydroxyisobutyric acid is also a renewable precursor of methacrylate through 2-HIB-CoA mutase-mediated biosynthesis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.89
HY-Y0124SNSC 16590-d6 -
Similarity Score 0.89
HY-W7055282-Bromo-2-methylpropanoic acid-d6 -
Similarity Score 0.85
HY-W699526Dimebutic acid-d6 -
Similarity Score 0.84
HY-W0158742-Hydroxy-2-methylbutanoic acid -
Similarity Score 0.84
HY-Y0376SDimethylolpropionic acid-d7 -
Similarity Score 0.83
HY-W012980S3Isovaleric acid-d7 -
Similarity Score 0.83
HY-113409R3-Hydroxyisovaleric acid (Standard) -
Similarity Score 0.82
HY-Y1150S2Pivalic acid-d9 -
Similarity Score 0.82
HY-Y1150Pivalic acid -
Explore the MedChemAI to find more analogs