416845-90-4
416845-90-4
Chemical Structure
DL-Homocysteine-d4
- CAS No.: 416845-90-4
- Formula:C4H5D4NO2S
- Molecular Weight:139.21
IUPAC Name: homocysteine-3,3,4,4-d4
InChIKey: FFFHZYDWPBMWHY-LNLMKGTHSA-N
SMILES: SC([2H])([2H])C([2H])([2H])C(N)C(O)=O
Biological Activity: DL-Homocysteine-d4 is the deuterium labeled DL-Homocysteine. DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain[1][2].
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DL-Homocysteine-d4 | 99.70% | DL-Homocysteine-d4 is the deuterium labeled DL-Homocysteine. DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. | ||||||||||||||||||||
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L-Homocysteine (Standard) | 98.83% | L-Homocysteine (Standard) is the analytical standard of L-Homocysteine. This product is intended for research and analytical applications. L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia. | ||||||||||||||||||||
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L-Homocysteine-d4 | 94.83% | L-Homocysteine-d4 is deuterium labeled L-Homocysteine (HY-W010347). L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia | ||||||||||||||||||||
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L-Homocysteine | 98.0% | L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. DL-Homocysteine, et al. Dual effect of DL-homocysteine and S-adenosylhomocysteine on brain synthesis of the glutamate receptor antagonist, kynurenic acid. J Neurosci Res. 2005 Feb 1;79(3):375-82. [Content Brief]
