42794-76-3
42794-76-3
Chemical Structure
Midodrine
Synonym(s): (±)-Midodrin
- CAS No.: 42794-76-3
- Formula:C12H18N2O4
- Molecular Weight:254.28
IUPAC Name: 2-amino-N-(2-(2,5-dimethoxyphenyl)-2-hydroxyethyl)acetamide
InChIKey: PTKSEFOSCHHMPD-UHFFFAOYSA-N
SMILES: O=C(NCC(C1=CC(OC)=CC=C1OC)O)CN
Biological Activity: Midodrine is a selective and orally active adrenergic α1-receptor agonist. Midodrine can strengthen vascular contraction. Midodrine can be used for the researches of cardiovascular disease, such as orthostatic hypotension[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Midodrine | 99.67% | Midodrine is a selective and orally active adrenergic α1-receptor agonist. Midodrine can strengthen vascular contraction. Midodrine can be used for the researches of cardiovascular disease, such as orthostatic hypotension. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-12749AMidodrine hydrochloride -
Similarity Score 0.98
HY-12749B(R)-Midodrine hydrochloride -
Similarity Score 0.77
HY-12749ASMidodrine-d6 hydrochloride -
Similarity Score 0.73
HY-B1298Methoxamine hydrochloride -
Similarity Score 0.70
HY-119868Butaxamine -
Similarity Score 0.70
HY-118470Butaxamine hydrochloride -
Similarity Score 0.67
HY-170743β-Hydroxy 2C-B hydrochloride -
Similarity Score 0.65
HY-131282Ivabradine impurity 2 -
Similarity Score 0.65
HY-N92851-(3-(1-Hydroxy-3-methylbutyl)-4-methoxyphenyl)ethan-1-one -
Explore the MedChemAI to find more analogs
References
- [1]. Criscuoli M, et al. Catecholamines released from the adrenal medulla exert a compensatory, protective effect at beta 2-adrenoceptors against Paf-induced death in mice. Br J Pharmacol. 1988 Jan;93(1):132-8. [Content Brief]
- [2]. Inchan A, et al. Anti-hypotensive effect of "Yahom Navakot" in rats with orthostatic hypotension. J Tradit Complement Med. 2021 Aug 3;12(2):180-189. [Content Brief]
- [3]. Lee YJ, et al. Stimulation of Alpha1-Adrenergic Receptor Ameliorates Cellular Functions of Multiorgans beyond Vasomotion through PPARδ. PPAR Res. 2020 Feb 1;2020:3785137. [Content Brief]
