449173-19-7
449173-19-7
Chemical Structure
VPC 23019
- CAS No.: 449173-19-7
- Formula:C17H29N2O5P
- Molecular Weight:372.40
IUPAC Name: (R)-2-amino-3-((3-octylphenyl)amino)-3-oxopropyl dihydrogen phosphate
InChIKey: MRUSUGVVWGNKFE-MRXNPFEDSA-N
SMILES: O=C(NC1=CC=CC(CCCCCCCC)=C1)[C@H](N)COP(O)(O)=O
Biological Activity: VPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VPC 23019 | 99.20% | VPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively). | ||||||||||||||||||||
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VPC 23019 (Standard) | ≥98% | VPC 23019 (Standard) is the analytical standard of VPC 23019 (HY-108490). This product is intended for research and analytical applications. VPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.81
HY-117892A(R)-VPC44116 -
Similarity Score 0.77
HY-W701470W140 hydrobromide -
Similarity Score 0.77
HY-101395RW146 (Standard) -
Similarity Score 0.70
HY-101395ARW146 TFA (Standard) -
Similarity Score 0.70
HY-136908W140 TFA -
Similarity Score 0.65
HY-116088W123 -
Similarity Score 0.60
HY-114061(R)-FTY 720P -
Similarity Score 0.60
HY-15381RFingolimod phosphate (Standard) -
Similarity Score 0.60
HY-15382FTY720 (S)-Phosphate -
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