(R)-VPC44116
(R)-VPC44116 is an isomer of VPC44116. VPC44116 is a selective S1P1 receptor antagonist.
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- CAS. Nr.: 925978-30-9
- Formel: C18H31N2O4P
- Molecular Weight:370.42
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | EC50 |
33 nM
Compound: 12d, VPC44116
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Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assay
Activity at human S1P5 receptor expressed in HEK293T cells by [35S]GTP-gamma-S binding assay
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[PMID: 17113298] |
Chemical Information
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CAS. Nr. 925978-30-9
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Molecular Weight 370.42
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Formel C18H31N2O4P
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SMILES
O=P(O)(O)CC[C@@H](N)C(NC1=CC(CCCCCCCC)=CC=C1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Li C, Li JN, Kays J, Guerrero M, Nicol GD. Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3. J Neuroinflammation. 2015;12:70. Published 2015 Apr 12. [Content Brief]
[2]. Awad AS, Ye H, Huang L, et al. Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney. Am J Physiol Renal Physiol. 2006;290(6):F1516-F1524. doi:10.1152/ajprenal.00311.2005 [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
(R)-VPC44116 Related Classifications
HY-117892A Related Classifications
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