1. GPCR/G Protein
  2. LPL Receptor
  3. VPC 23019

VPC 23019 

Cat. No.: HY-108490
Handling Instructions

VPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively).

For research use only. We do not sell to patients.

VPC 23019 Chemical Structure

VPC 23019 Chemical Structure

CAS No. : 449173-19-7

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Description

VPC 23019, an aryl amide-containing Sphingosine 1-phosphate (S1P) analog, is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively) and an agonist at the S1P4 and S1P5 receptors (pEC50= 6.58 and 7.07, respectively)[1].

IC50 & Target

pKi: 7.86 (S1P1); 5.93 (S1P3). pEC50: 6.58 (S1P1); 7.07 (S1P3)[1]

Molecular Weight

372.40

Formula

C₁₇H₂₉N₂O₅P

CAS No.

449173-19-7

SMILES

O=C(NC1=CC=CC(CCCCCCCC)=C1)[[email protected]](N)COP(O)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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VPC 23019
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HY-108490
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