471-80-7
471-80-7
Chemical Structure
Steviol
- CAS No.: 471-80-7
- Formula:C20H30O3
- Molecular Weight:318.45
IUPAC Name: (4R,4aS,6aR,9S,11aR,11bS)-9-hydroxy-4,11b-dimethyl-8-methylenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid
InChIKey: QFVOYBUQQBFCRH-VQSWZGCSSA-N
SMILES: C[C@@]1(C(O)=O)CCC[C@@]2(C)[C@@]3([H])[C@@]4(CC([C@@](CC3)(O)C4)=C)CC[C@]12[H]
Biological Activity: Steviol is the main metabolite of steviol glycosides and an inhibitor of AQP2/CFTR. Steviol slows down the growth of renal cysts by inhibiting the activity of CFTR, reducing the expression of AQP2, and promoting the degradation of AQP2 and CFTR. Steviol can be used in the research of polycystic kidney disease[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Steviol | 99.85% | Steviol is the main metabolite of steviol glycosides and an inhibitor of AQP2/CFTR. Steviol slows down the growth of renal cysts by inhibiting the activity of CFTR, reducing the expression of AQP2, and promoting the degradation of AQP2 and CFTR. Steviol can be used in the research of polycystic kidney disease. | ||||||||||||||||||||
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Steviol (Standard) | ≥98% | Steviol (Standard) is the analytical standard of Steviol (HY-N2057). This product is intended for research and analytical applications. Steviol is the main metabolite of steviol glycosides and an inhibitor of AQP2/CFTR. Steviol slows down the growth of renal cysts by inhibiting the activity of CFTR, reducing the expression of AQP2, and promoting the degradation of AQP2 and CFTR. Steviol can be used in the research of polycystic kidney disease. | ||||||||||||||||||||
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Toonaciliatin M | Toonaciliatin M (compound 6) is a pmaradiene-type diterpenoid that can be isolated from Toona ciliate. Toonaciliatin M show antifungal activity against Trichophyton rubrum with an MIC value of 12.5 µg/mL. | |||||||||||||||||||||
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Sventenic acid | Sventenic acid is a Diterpenoids product that can be isolated from the herbs of Rabdosia excisa. | |||||||||||||||||||||
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Kaurenoic acid (Standard) | ≥98% | Kaurenoic acid (Standard) is the analytical standard of Kaurenoic acid. This product is intended for research and analytical applications. Kaurenoic acid is a diterpene from Sphagneticola trilobata, inhibits Inflammatory Pain by the inhibition of cytokine production and activation of the NO–cyclic GMP–PKG–ATP-sensitive potassium channel signaling pathway. | ||||||||||||||||||||
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Pterokaurene L3 | Pterokaurene L3 is a Diterpenoids product that can be isolated from the herbs of Wedelia trilobata. | |||||||||||||||||||||
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Steviol-15-ene | Steviol-15-ene is a Δ15-double bond isomer of steviol, a tetracyclic diterpenoid. Steviol-15-ene undergoes 7β-hydroxylation by Gibberella fujikuroi to form methyl ent-7α,13-dihydroxykaur-15-en-19-oate. | |||||||||||||||||||||
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Deacetylxylopic acid | Deacetylxylopic acid (ent-15α-Hydroxykaurenoic acid) is a Diterpene product that can be isolated from Blumea eriantha. | |||||||||||||||||||||
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(4α,11β,15β)-11,15-Dihydroxykaur-16-en-19-oic acid | (4α,11β,15β)-11,15-Dihydroxykaur-16-en-19-oic acid is a compound isolated from the Tunisian Pulicaria laciniata (Coss.et Kral.) Thell. flowers. | |||||||||||||||||||||
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ent-16β,17-Dihydroxykauran-19-oic acid | 98.0% | ent-16β,17-Dihydroxykauran-19-oic acid is an anti-inflammatory agent, which can be isolated from Siegesbeckia pubescens herb. ent-16β,17-Dihydroxykauran-19-oic acid inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglia. | ||||||||||||||||||||
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Grandifloric acid | Grandifloric acid is a Diterpenoids product that can be isolated from the herbs of Siegesbeckia orientalis L.. | |||||||||||||||||||||
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ent-13,16β,17-Trihydroxykauran-19-oic acid | ent-13,16β,17-Trihydroxykauran-19-oic acid is a natural diterpene. | |||||||||||||||||||||
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References
- [1]. Noitem R, et al. Steviol slows renal cyst growth by reducing AQP2 expression and promoting AQP2 degradation. Biomed Pharmacother. 2018 May;101:754-762. [Content Brief]
- [2]. Melis MS, et al. Steviol effect, a glycoside of Stevia rebaudiana, on glucose clearances in rats. Braz J Biol. 2009 May;69(2):371-4. [Content Brief]
