475110-96-4
475110-96-4
Chemical Structure
ZSTK474
- CAS No.: 475110-96-4
- Formula:C19H21F2N7O2
- Molecular Weight:417.41
IUPAC Name: 4,4'-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5-triazine-2,4-diyl)dimorpholine
InChIKey: HGVNLRPZOWWDKD-UHFFFAOYSA-N
SMILES: FC(C1=NC2=C(N1C3=NC(N4CCOCC4)=NC(N5CCOCC5)=N3)C=CC=C2)F
Biological Activity: ZSTK474 is an ATP-competitive pan-class I PI3K inhibitor with IC50s of 16 nM, 44 nM, 4.6 nM and 49 nM for PΙ3Κα, PI3Kβ, PI3Kδ and PI3Kγ, respectively.
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ZSTK474 | 99.71% | ZSTK474 is an ATP-competitive pan-class I PI3K inhibitor with IC50s of 16 nM, 44 nM, 4.6 nM and 49 nM for PΙ3Κα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. | ||||||||||||||||||||
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Keywords
