480-00-2
480-00-2
Chemical Structure
Eleutherol
- CAS No.: 480-00-2
- Formula:C14H12O4
- Molecular Weight:244.24
IUPAC Name: (R)-4-hydroxy-5-methoxy-3-methylnaphtho[2,3-c]furan-1(3H)-one
InChIKey: KNLHGXVYZRQSJZ-SSDOTTSWSA-N
SMILES: O=C1O[C@H](C)C2=C(O)C3=C(OC)C=CC=C3C=C12
Biological Activity: Eleutherol is a naphthalene isolated from E. americana with antifungal activities[1]. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL[1]. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM[2].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Eleutherol | 99.99% | Eleutherol is a naphthalene isolated from E. americana with antifungal activities. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM. | ||||||||||||||||||||
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Aβ1–42 aggregation inhibitor 2 | Aβ1–42 aggregation inhibitor 2 (compound 7c) is a potent inhibitor of Aβ1-42 aggregation that plays an important role in Alzheimer's disease research. Aβ1–42 aggregation inhibitor 2 displays excellent antioxidant, metal ions chelating, oxidative stress alleviation, neuroprotective and anti-neuroinflammatory activities. | |||||||||||||||||||||
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Torachrysone | Torachrysone (Nakahalene; Trachrysone), a naphthalene, can be isolated from Cassia tora L. | |||||||||||||||||||||
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Thunberginol C | Thunberginol C is an orally active, selective, and non-competitive inhibitor of AChE and BChE, with IC50 values of 41.96 and 42.36 μM, respectively. Thunberginol C exerts cytoprotective, pro-collagen type I restorative, MMP-1 inhibitory, hyaluronic acid restorative, anti-photoaging effects in skin cells. Thunberginol C exerts neuroprotective, anxiolytic, TNF-α inhibitory, neuroinflammation inhibitory, and oxidative stress inhibitory effects. Thunberginol C can be used for the research of Alzheimer’s disease, UVB-induced skin photoaging, allergic reactions, oral bacterial infections, and stress-induced anxiety. | |||||||||||||||||||||
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1-Hydroxy-4-methoxy-2-naphthoic acid | 1-Hydroxy-4-methoxy-2-naphthoic acid is a herbicidal compound found in Streptosporangium cinnabarinum ATCC 31213. | |||||||||||||||||||||
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3-(2,6-Dihydroxyphenyl)-4-hydroxy-6-methylisobenzofuran-1(3H)-one | 3-(2,6-Dihydroxyphenyl)-4-hydroxy-6-methylisobenzofuran-1(3H)-one is a polyketide compound found in the mangrove endophytic fungus Phomopsis sp. xy21. 3-(2,6-Dihydroxyphenyl)-4-hydroxy-6-methylisobenzofuran-1(3H)-one shows neuroprotective activity against Corticosterone (HY-B1618)-induced injury in neuronal cells. | |||||||||||||||||||||
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(+)-Hydrangenol monomethyl ether | (+)-Hydrangenol monomethyl ether is a hydrangenol-monomethyl ether (+)-enantiomer found in axenic cultures of the liverwort Plagiochila adianthoides. | |||||||||||||||||||||
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Hydrangenol | 99.62% | Hydrangenol is an orally active antiphotoaging compound. It can be isolated from Hydrangea serrata leaves. Hydrangenol prevents wrinkle formation by reducing MMP and inflammatory cytokine expression and increasing moisturizing factors and antioxidant genes level. | ||||||||||||||||||||
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Nepodin (Standard) | ≥98% | Nepodin (Standard) is the analytical standard of Nepodin. This product is intended for research and analytical applications. Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus.Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK.Nepodin (Musizin) has antidiabetic and antimalarial activities. | ||||||||||||||||||||
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Dihydromollugin | Dihydromollugin is a natural naphthoic acid ester. | |||||||||||||||||||||
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Phyllodulcin | 99.75% | Phyllodulcin is an orally active sweetener found in Hydrangea macrophylla var. thunbergii. Phyllodulcin acts as a non-selective phosphodiesterase inhibitor and exerts anti-allergic effects by suppressing lymphocyte activation. Phyllodulcin can be used to combat obesity by regulating levels of leptin, fat browning-related genes, and hypothalamic BDNF-TrkB signaling. | ||||||||||||||||||||
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References
- [1]. Adriana Campos, et al. Antifungal Activity of Pyranonaphthoquinones Obtained from Cipura paludosa Bulbs. Nat Prod Commun. 2015 Sep;10(9):1589-92. [Content Brief]
- [2]. Tomohiro Ieyama,et al.α-Glucosidase inhibitors from the bulb of Eleutherine americana. Food Chem.2011 Sep 15;128(2):308-11. [Content Brief]
