480439-73-4
Chemical Structure
TFB-TBOA
Synonym(s): CF3-Bza-TBOA
- CAS No.: 480439-73-4
- Formula:C19H17F3N2O6
- Molecular Weight:426.34
IUPAC Name: (2S,3S)-2-amino-3-((3-(4-(trifluoromethyl)benzamido)benzyl)oxy)succinic acid
InChIKey: LPWONNPEPDHEAI-GJZGRUSLSA-N
SMILES: O=C(C1=CC=C(C=C1)C(F)(F)F)NC2=CC(CO[C@H](C(O)=O)[C@H](N)C(O)=O)=CC=C2
Biological Activity: TFB-TBOA (CF3-Bza-TBOA) is a potent glutamate transporter blocker that potently suppresses the activity of glial transporters. TFB-TBOA shows IC50 values of 22, 17, and 300 nM for glutamate transporters EAAT1, EAAT2, and EAAT3 respectively in an uptake assay using cells transiently expressing EAATs[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TFB-TBOA | 99.96% | TFB-TBOA (CF3-Bza-TBOA) is a potent glutamate transporter blocker that potently suppresses the activity of glial transporters. TFB-TBOA shows IC50 values of 22, 17, and 300 nM for glutamate transporters EAAT1, EAAT2, and EAAT3 respectively in an uptake assay using cells transiently expressing EAATs. | ||||||||||||||||||||
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Keywords
