480439-73-4
Chemical Structure
TFB-TBOA
Synonym(s): CF3-Bza-TBOA
- CAS No.: 480439-73-4
- Formula:C19H17F3N2O6
- Molecular Weight:426.34
IUPAC Name: (2S,3S)-2-amino-3-((3-(4-(trifluoromethyl)benzamido)benzyl)oxy)succinic acid
InChIKey: LPWONNPEPDHEAI-GJZGRUSLSA-N
SMILES: O=C(C1=CC=C(C=C1)C(F)(F)F)NC2=CC(CO[C@H](C(O)=O)[C@H](N)C(O)=O)=CC=C2
Biological Activity: TFB-TBOA (CF3-Bza-TBOA) is a potent glutamate transporter blocker that potently suppresses the activity of glial transporters. TFB-TBOA shows IC50 values of 22, 17, and 300 nM for glutamate transporters EAAT1, EAAT2, and EAAT3 respectively in an uptake assay using cells transiently expressing EAATs[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
TFB-TBOA | 99.96% | TFB-TBOA (CF3-Bza-TBOA) is a potent glutamate transporter blocker that potently suppresses the activity of glial transporters. TFB-TBOA shows IC50 values of 22, 17, and 300 nM for glutamate transporters EAAT1, EAAT2, and EAAT3 respectively in an uptake assay using cells transiently expressing EAATs. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.59
HY-159484Hsp110/sGC-modulator-1 -
Similarity Score 0.58
HY-134753Teriflunomide impurity 3 -
Similarity Score 0.56
HY-14422SR1078 -
Similarity Score 0.55
HY-107522BDL-TBOA ammonium -
Similarity Score 0.55
HY-W5869834-(4-Carboxybenzamido)benzoic acid -
Similarity Score 0.54
HY-107522DL-TBOA -
Similarity Score 0.54
HY-112731TFAP -
Similarity Score 0.54
HY-132869MEIS-IN-1 -
Similarity Score 0.54
HY-138557AKR1C3-IN-4 -
Explore the MedChemAI to find more analogs
