485-72-3
485-72-3
Chemical Structure
Formononetin
Synonym(s): Biochanin B; Flavosil; Formononetol
- CAS No.: 485-72-3
- Formula:C16H12O4
- Molecular Weight:268.26
IUPAC Name: 7-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one
InChIKey: HKQYGTCOTHHOMP-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC=C(OC)C=C2)=COC3=CC(O)=CC=C13
Biological Activity: Formononetin is a potent FGFR2 inhibitor with an IC50 of ~4.31 μM. Formononetin potently inhibits angiogenesis and tumor growth[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Formononetin | 99.21% | Formononetin is a potent FGFR2 inhibitor with an IC50 of ~4.31 μM. Formononetin potently inhibits angiogenesis and tumor growth. | ||||||||||||||||||||
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Formononetin (Standard) | 98.79% | Formononetin (Standard) is the analytical standard of Formononetin. This product is intended for research and analytical applications. Formononetin is a potent FGFR2 inhibitor with an IC50 of ~4.31 μM. Formononetin potently inhibits angiogenesis and tumor growth. | ||||||||||||||||||||
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Formononetin-d3-1 | 99.67% | Formononetin-d3-1 is the deuterium-labeled Formononetin (HY-N0183). | ||||||||||||||||||||
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Texasin | 99.14% | Texasin is a natural product that can be isolated from Baptisia australis. | ||||||||||||||||||||
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Biochanin A | 99.33% | Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively. | ||||||||||||||||||||
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Ipriflavone metabolites IV | Ipriflavone metabolites IV is a metabolite of Ipriflavone (HY-N0094). | |||||||||||||||||||||
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Daidzein (Standard) | 98.65% | Daidzein (Standard) is the analytical standard of Daidzein. This product is intended for research and analytical applications. Daidzein is a soy isoflavone, which acts as a PPAR activator. | ||||||||||||||||||||
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Calycosin (Standard) | ≥98% | Calycosin (Standard) is the analytical standard of Calycosin. This product is intended for research and analytical applications. Calycosin is a compound that can be isolated from Radix Astragali. Calycosin has strong antioxidant, anti-inflammatory and apoptosis-modulating effects. Calycosin can be used for the research of ovarian cancer and breast cancer. | ||||||||||||||||||||
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3'-Methoxydaidzein | 99.67% | 3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels. | ||||||||||||||||||||
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4',7-Dimethoxyisoflavone | 98.61% | 4',7-Dimethoxyisoflavone is isolated from the leaves of Albizzia lebbeck, which shows antifungal activity. | ||||||||||||||||||||
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7-Methoxyisoflavone | 99.47% | 7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK). | ||||||||||||||||||||
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Isoformononetin (Standard) | ≥98% | Isoformononetin (Standard) is the analytical standard of Isoformononetin. This product is intended for research and analytical applications. Isoformononetin is an analog of Daidzein (HY-N0019) and has immunoprotective effects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions. | ||||||||||||||||||||
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7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one | 7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one is a dual agonist of PPARα and PPARγ, with an EC50 of 23.10 μM for human PPARα and an EC50 of 22.29 μM for human PPARγ. 7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one regulates the expression of lipid metabolism-related genes via PPARα, and modulates the expression of genes associated with glucose homeostasis and adipogenesis via PPARγ. 7-Hydroxy-3-(3-methoxyphenyl)-4H-chromen-4-one can be used in the research of type 2 diabetes and metabolic syndrome. | |||||||||||||||||||||
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