516-41-6
516-41-6
Chemical Structure
5α-Dihydrocortisol
Synonym(s): 5α-DHF
- CAS No.: 516-41-6
- Formula:C21H32O5
- Molecular Weight:364.48
IUPAC Name: (5S,8S,9S,10S,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: ACSFOIGNUQUIGE-SERXDUEGSA-N
SMILES: C[C@@]12[C@](CC[C@]2(O)C(CO)=O)([H])[C@@]3([H])[C@@]([C@H](C1)O)([H])[C@@]4([C@@](CC(CC4)=O)([H])CC3)C
Biological Activity: 5α-Dihydrocortisol (5α-DHF), a metabolite of Hydrocortisone (Cortisol) (HY-N0583), is a steroid hormone. 5α-Dihydrocortisol can enhance the mineralocorticoid activity of aldosterone[1][2].
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5α-Dihydrocortisol | 98.17% | 5α-Dihydrocortisol (5α-DHF), a metabolite of Hydrocortisone (Cortisol) (HY-N0583), is a steroid hormone. 5α-Dihydrocortisol can enhance the mineralocorticoid activity of aldosterone. | ||||||||||||||||||||
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5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d4 | 5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5-d4 is the deuterium labeled 5α-Pregnan-11β,17α,21-triol-3,20-dione-1,2,4,5. | |||||||||||||||||||||
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References
- [1]. Adam WR, et al. Amplification of the action of aldosterone by 5 alpha-dihydrocortisol. Endocrinology. 1978 Aug;103(2):465-71. [Content Brief]
- [2]. Mikami H, et al. The effect of 5 alpha-dihydrocortisol on the blood pressure of rats treated with deoxycorticosterone acetate and salt. Endocrinol Jpn. 1980 Dec;27(6):769-73. [Content Brief]
