532-91-2
532-91-2
Chemical Structure
Coixol
Synonym(s): 6-Methoxy-2-benzoxazolinone; 6-MBOA
- CAS No.: 532-91-2
- Formula:C8H7NO3
- Molecular Weight:165.15
IUPAC Name: 6-methoxybenzo[d]oxazol-2(3H)-one
InChIKey: MKMCJLMBVKHUMS-UHFFFAOYSA-N
SMILES: O=C1OC2=CC(OC)=CC=C2N1
Biological Activity: Coixol (6-Methoxy-2-benzoxazolinone; 6-MBOA) is a potent and orally active anti-inflammatory agent. Coixol decreases the iNOS protein expression. Coixol inhibits the production of TNF-α, IL-6, and IL-1β. Coixol improves glucose tolerance and plasma insulin. Coixol decreases the blood glucose level[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Coixol | 98.56% | Coixol (6-Methoxy-2-benzoxazolinone; 6-MBOA) is a potent and orally active anti-inflammatory agent. Coixol decreases the iNOS protein expression. Coixol inhibits the production of TNF-α, IL-6, and IL-1β. Coixol improves glucose tolerance and plasma insulin. Coixol decreases the blood glucose level. | ||||||||||||||||||||
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Coixol (Standard) | 98.67% | Coixol (6-Methoxy-2-benzoxazolinone; 6-MBOA) is a potent and orally active anti-inflammatory agent. Coixol decreases the iNOS protein expression. Coixol inhibits the production of TNF-α, IL-6, and IL-1β. Coixol improves glucose tolerance and plasma insulin. Coixol decreases the blood glucose level. | ||||||||||||||||||||
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References
- [1]. Yusheng Hu, et al. Coixol Suppresses NF-κB, MAPK Pathways and NLRP3 Inflammasome Activation in Lipopolysaccharide-Induced RAW 264.7 Cells. Molecules [Content Brief]
- [2]. Cui E, et al. Discovery of Coixol Derivatives as Potent Anti-inflammatory Agents. J Nat Prod. 2023 Aug 25;86(8):1950-1959. [Content Brief]
- [3]. Hameed A, et al. Coixol amplifies glucose-stimulated insulin secretion via cAMP mediated signaling pathway. Eur J Pharmacol. 2019 Sep 5;858:172514. [Content Brief]
Keywords
