533-87-9
Chemical Structure
Aleuritic acid
Synonym(s): (±)-erythro-Aleuritic acid; α-Aleuritic acid
- CAS No.: 533-87-9
- Formula:C16H32O5
- Molecular Weight:304.42
IUPAC Name: (9R,10S)-9,10,16-trihydroxyhexadecanoic acid
InChIKey: MEHUJCGAYMDLEL-CABCVRRESA-N
SMILES: OCCCCCC[C@H](O)[C@H](O)CCCCCCCC(O)=O
Biological Activity: Aleuritic acid ((±)-erythro-Aleuritic acid; α-Aleuritic acid) is a polyhydroxy fatty acid found in plant cutin and shellac. Aleuritic acid disrupts the Mycobacterium tuberculosis Nei2-β-clamp (DnaN) interaction and binds to the Mycobacterium tuberculosis β-clamp without affecting the intrinsic DNA glycosylase activity of Nei2. Aleuritic acid self-assembles with pectin to form cutin body nanoparticles. Aleuritic acid is the major component of Croton crassifolius. Aleuritic acid is used in mycobacterial and fragrance-related research[1][2][3].
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Aleuritic acid | 99.73% | Aleuritic acid ((±)-erythro-Aleuritic acid; α-Aleuritic acid) is a polyhydroxy fatty acid found in plant cutin and shellac. Aleuritic acid disrupts the Mycobacterium tuberculosis Nei2-β-clamp (DnaN) interaction and binds to the Mycobacterium tuberculosis β-clamp without affecting the intrinsic DNA glycosylase activity of Nei2. Aleuritic acid self-assembles with pectin to form cutin body nanoparticles. Aleuritic acid is the major component of Croton crassifolius. Aleuritic acid is used in mycobacterial and fragrance-related research. | ||||||||||||||||||||
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Aleuritic acid (Standard) | ≥98% | Aleuritic acid (Standard) ((±)-erythro-Aleuritic acid (Standard); α-Aleuritic acid (Standard)) is the analytical standard of Aleuritic acid (HY-N7076). This product is intended for research and analytical applications. Aleuritic acid ((±)-erythro-Aleuritic acid; α-Aleuritic acid) is a polyhydroxy fatty acid found in plant cutin and shellac. Aleuritic acid disrupts the Mycobacterium tuberculosis Nei2-β-clamp (DnaN) interaction and binds to the Mycobacterium tuberculosis β-clamp without affecting the intrinsic DNA glycosylase activity of Nei2. Aleuritic acid self-assembles with pectin to form cutin body nanoparticles. Aleuritic acid is the major component of Croton crassifolius. Aleuritic acid is used in mycobacterial and fragrance-related research. | ||||||||||||||||||||
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References
- [1]. Guzman-Puyol S, et al. Pectin-lipid self-assembly: influence on the formation of polyhydroxy fatty acids nanoparticles. PloS one. 2015;10(4):e0124639.
- [2]. Lata K, et al. Mycobacterium tuberculosis Endonuclease VIII 2 (Nei2) forms a prereplicative BER complex with DnaN: Identification, characterization, and disruption of complex formation. Molecular microbiology. 2022 Feb;117(2):320-333.
- [3]. Biswas S. Preparation of environment friendly composites from effluent of aleutitic acid industry and modified betel-nut fiber[J]. Int. J. Curr. Res. Chem. Pharma. Sci, 2014, 1(6): 50-55.
