54-06-8
54-06-8
Chemical Structure
Adrenochrome
Synonym(s): Adraxone
- CAS No.: 54-06-8
- Formula:C9H9NO3
- Molecular Weight:179.17
IUPAC Name: 3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione
InChIKey: RPHLQSHHTJORHI-UHFFFAOYSA-N
SMILES: O=C1C=C2C(CN(C2=CC1=O)C)O
Biological Activity: Adrenochrome (Adraxone) is an oxidation product of Epinephrine. Adrenochrome is a potent coronary constricting agent in the rat heart. Adrenochrome can be used for neurological disorder research[1][2][3].
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Adrenochrome | 99.22% | Adrenochrome (Adraxone) is an oxidation product of Epinephrine. Adrenochrome is a potent coronary constricting agent in the rat heart. Adrenochrome can be used for neurological disorder research. | ||||||||||||||||||||
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Adrenochrome (Standard) | ≥98% | Adrenochrome (Standard) is the analytical standard of Adrenochrome. This product is intended for research and analytical applications. | ||||||||||||||||||||
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AB 5046B | AB 5046B is a chlorosis-inducing substance can be isolated from Nodulisporium sp. | |||||||||||||||||||||
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4-Hydroxyisophorone | 95.96% | 4-Hydroxyisophorone is a derivative of Abscisic acid (HY-100560). 4-Hydroxyisophorone a weak inhibitory effect on plant growth. | ||||||||||||||||||||
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Cinerolone | Cinerolone is a hydroxylated product of cinerone that can be hydroxylated through a microbial system. | |||||||||||||||||||||
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trans-4-Hydroxy-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-one | trans-4-Hydroxy-3-methyl-6-(1-methylethyl)-2-cyclohexen-1-one (Compound 5) is a monoterpenoid compound found in the fruits of Amomum kravanh. | |||||||||||||||||||||
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(-)-3-Dehydroshikimic acid | 98.35% | (-)-3-Dehydroshikimic acid (3-DHS) is an intermediate of the Shikimate pathway. (-)-3-Dehydroshikimic acid is found in vegetables and fruits. (-)-3-Dehydroshikimic acid accumulates in bacterial mutants, serves as a precursor of aromatic metabolites, and competitively interferes with the growth response of mutant bacteria to Shikimic acid (HY-N0130). (-)-3-Dehydroshikimic acid exhibits weak antioxidant activity in liposomes and corn oil oil-in-water emulsions. | ||||||||||||||||||||
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6-Hydroxytropinone (Standard) | ≥98% | 6-Hydroxytropinone (Standard) is the analytical standard of 6-Hydroxytropinone. This product is intended for research and analytical applications. 6-Hydroxytropinone is a cyclic hydroxylation product of Tropinone (HY-Y0135), and serves as an indicator for tropane alkaloid metabolism in plants or microorganisms. 6-Hydroxytropinone itself has no significant anticholinergic toxicity, nor does it act as a substrate for Tropine (HY-N7061) dehydrogenase. | ||||||||||||||||||||
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Toluquinone | Toluquinone is a Toluquinol analogue. Toluquinone shows lower growth inhibitory activity against a panel of cancer cell lines of breast adenocarcinoma, promyelocytic leukemia, glioblastoma, fibrosarcoma, and colorectal adenocarcinoma than Toluquinol. | |||||||||||||||||||||
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2,6-Dimethylbenzoquinone | 99.36% | 2,6-Dimethylbenzoquinone (2,6-DMBQ) is a benzoquinone derivative. 2,6-Dimethylbenzoquinone promotes Photosystem II-mediated photoelectrochemical water oxidation via electron transfer between spinach chloroplast Photosystem II membranes and carbon paste electrodes, and accepts electrons from Photosystem II during oxygen evolution assays. 2,6-Dimethylbenzoquinone undergoes direct photolysis in aqueous solution under 365 nm conditions, producing 2,6-dimethylhydroquinone and 3-hydroxy-2,6-dimethylbenzoquinone. | ||||||||||||||||||||
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2,5-Dimethyl-1,4-benzoquinone | 99.35% | 2,5-Dimethyl-1,4-benzoquinone is a jack bean urease (HY-P2767) inhibitor (IC50: 0.98 μM). 2,5-Dimethyl-1,4-benzoquinone can be used in the study of soil urease activity in agriculture. | ||||||||||||||||||||
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Trimethylbenzoquinone | 99.87% | Trimethylbenzoquinone (Compound 5) is a methylated benzoquinone. Trimethylbenzoquinone exhibits moderate cytotoxicity against K562 cells, with its IC50 being 0.75 μM. Trimethylbenzoquinone is completely unable to cause inter-strand DNA cross-linking and cannot alkylate DNA guanines. Trimethylbenzoquinone can be used to study the relationship between the nitrogen heterocyclic group and DNA cross-linking. | ||||||||||||||||||||
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References
- [1]. M Karmazyn,, et al. Adrenochrome-induced coronary artery constriction in the rat heart. J Pharmacol Exp Ther. 1981 Oct;219(1):225-30. [Content Brief]
- [2]. S Takeo,et al. Effects of adrenochrome on calcium accumulating and adenosine triphosphatase activities of the rat heart microsomes. J Pharmacol Exp Ther. 1980 Sep;214(3):688-93. [Content Brief]
- [3]. Koji Ueda, et al. Catecholamine oxidation-mediated transcriptional inhibition in Mn neurotoxicity. J Toxicol Sci. 2020;45(10):619-624. [Content Brief]
