54573-75-0
54573-75-0
Chemical Structure
Doxercalciferol
Synonym(s): 1.alpha.-Hydroxyvitamin D2
- CAS No.: 54573-75-0
- Formula:C28H44O2
- Molecular Weight:412.65
IUPAC Name: (1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol
InChIKey: HKXBNHCUPKIYDM-CGMHZMFXSA-N
SMILES: C=C1[C@H](C[C@@H](C/C1=C/C=C2[C@]3([C@@](C)([C@H](CC3)[C@@H](/C=C/[C@@H](C(C)C)C)C)CCC/2)[H])O)O
Biological Activity: Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Doxercalciferol | 99.85% | Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease. | ||||||||||||||||||||
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Doxercalciferol (Standard) | ≥98% | Doxercalciferol (Standard) is the analytical standard of Doxercalciferol. This product is intended for research and analytical applications. Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease. | ||||||||||||||||||||
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Doxercalciferol-d3 | Doxercalciferol-d33 is the deuterated form of Doxercalciferol, which is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA). | |||||||||||||||||||||
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Doxercalciferol-d6 | Doxercalciferol-d6 (1.alpha.-Hydroxyvitamin D2-d6) is deuterium labeled Doxercalciferol. Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease. | |||||||||||||||||||||
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Calcipotriol | 99.90% | Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor. | ||||||||||||||||||||
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1alpha-Hydroxy VD4 | 98.0% | 1alpha-Hydroxy VD4, a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells. | ||||||||||||||||||||
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24R-Calcipotriol | 94.85% | 24R-Calcipotriol (PRI 2202; Impurity D of Calcipotriol), an isomer of Calcipotriol (HY-10001), is a synthetic vitamin D analog. 24R-Calcipotriol exhibits synergistic antiproliferative effects with low-dose cytostatics in in vitro. 24R-Calcipotriol produces tumor growth inhibition when combined with Cyclophosphamide (HY-17420) and Cisplatin (HY-17394) in mice models. 24R-Calcipotriol can increase serum calcium levels and reduce blood leukocyte counts. 24R-Calcipotriol can be used for the research of mammary cancer and Lewis lung cancer. | ||||||||||||||||||||
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Ercalcitriol (Standard) | 95.85% | Ercalcitriol (Standard) is the analytical standard of Ercalcitriol. This product is intended for research and analytical applications. Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2. | ||||||||||||||||||||
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Calcipotriol Impurity C | 99.11% | Calcipotriol Impurity C is an impurity of Calcipotriol (HY-10001). Calcipotriol is a synthetic vitamin D3 analogue with high affinity for the vitamin D receptor. | ||||||||||||||||||||
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trans-Doxercalciferol | 98.20% | trans-Doxercalciferol is an isomer of Doxercalciferol (HY-32348). Doxercalciferol is a vitamin D receptor agonist. Doxercalciferol reduces proteinuria, podocyte injury, mesangial expansion, extracellular matrix accumulation, macrophage infiltration, oxidative stress, proinflammatory cytokines, profibrotic growth factors, renal neutral lipid accumulation, albuminuria and glomerulosclerosis. Doxercalciferol alleviates high-salt diet-induced myocardial hypertrophy. trans-Doxercalciferol is used for the research of diet-induced obesity-related nephropathy, diabetic nephropathy, myocardial hypertrophy, cardiac dysfunction and secondary hyperparathyroidism. | ||||||||||||||||||||
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Vitamin D2 | 99.11% | Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D. |
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5,6-trans-Vitamin D2 (Standard) | ≥98% | 5,6-trans-Vitamin D2 (Standard) is the analytical standard of 5,6-trans-Vitamin D2. This product is intended for research and analytical applications. 5,6-trans-Vitamin D2 is the isomer of Vitamin D2. | ||||||||||||||||||||
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(R)-Vitamin D2 | 98.67% | (R)-Vitamin D2 is the isomer of Vitamin D2 (HY-76542), and can be used as an experimental control. Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D. |
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Impurity of Doxercalciferol | Impurity of Doxercalciferol is an impurity of doxercalciferol, which is a synthetic analog of ergocalciferol (vitamin D2), used as a agent for secondary hyperparathyroidism and metabolic bone disease, and it suppresses parathyroid synthesis and secretion. | |||||||||||||||||||||
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