548-37-8
Chemical Structure
Verbenalin
- CAS No.: 548-37-8
- Formula:C17H24O10
- Molecular Weight:388.37
IUPAC Name: methyl (1S,4aS,7S,7aR)-7-methyl-5-oxo-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate
InChIKey: HLXRWTJXGMHOFN-XJSNKYLASA-N
SMILES: O=C(C1=CO[C@@H](O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)[C@@]3([H])[C@]1([H])C(C[C@@H]3C)=O)OC
Biological Activity: Verbenalin is an orally active terpenoid glycoside that can be extracted from the medicinal plant Verbena officinalis. Verbenalin has anti-inflammatory, antiviral, and neuroprotective effects. Verbenalin has a strong binding affinity to the nsp-12 protein of the SARS-CoV-2 virus. Verbenalin can be used in the research of inflammatory and nervous system diseases such as hepatitis and Alzheimer's disease[1][2][3][4][5].
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Verbenalin | 99.93% | Verbenalin is an orally active terpenoid glycoside that can be extracted from the medicinal plant Verbena officinalis. Verbenalin has anti-inflammatory, antiviral, and neuroprotective effects. Verbenalin has a strong binding affinity to the nsp-12 protein of the SARS-CoV-2 virus. Verbenalin can be used in the research of inflammatory and nervous system diseases such as hepatitis and Alzheimer's disease. | ||||||||||||||||||||
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Verbenalin (Standard) | ≥98% | Verbenalin (Standard) is the analytical standard of Verbenalin. This product is intended for research and analytical applications. Verbenalin is an orally active terpenoid glycoside that can be extracted from the medicinal plant Verbena officinalis. Verbenalin has anti-inflammatory, antiviral, and neuroprotective effects. Verbenalin has a strong binding affinity to the nsp-12 protein of the SARS-CoV-2 virus. Verbenalin can be used in the research of inflammatory and nervous system diseases such as hepatitis and Alzheimer's disease. | ||||||||||||||||||||
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- [1]. Lim J, et al. Verbenalin Reduces Amyloid-Beta Peptide Generation in Cellular and Animal Models of Alzheimer's Disease. Molecules. 2022 Dec 8;27(24):8678. [Content Brief]
- [2]. Miao M, et al. Effects of verbenalin on prostatitis mouse model. Saudi J Biol Sci. 2016 Jan;23(1):S148-57. [Content Brief]
- [3]. Cao L, et al. The protective role of verbenalin in rat model of focal cerebral ischemia reperfusion. Saudi J Biol Sci. 2018 Sep;25(6):1170-1177. [Content Brief]
- [4]. Hafiza Salaha Mahrosh, et al. An in silico approach to target RNA-dependent RNA polymerase of COVID-19 with naturally occurring phytochemicals. Environ Dev Sustain. 2021 Apr 3;1-14. [Content Brief]
- [5]. Dong J, et al. Verbenalin attenuates hepatic damage and mitochondrial dysfunction in alcohol-associated steatohepatitis by regulating MDMX/PPARα-mediated ferroptosis. J Ethnopharmacol. 2023 May 10;307:116227. [Content Brief]
Keywords
