552-59-0
552-59-0
Chemical Structure
Prunetin
- CAS No.: 552-59-0
- Formula:C16H12O5
- Molecular Weight:284.26
IUPAC Name: 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one
InChIKey: KQMVAGISDHMXJJ-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC=C(O)C=C2)=COC3=CC(OC)=CC(O)=C13
Biological Activity: Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor[1][2].
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Prunetin | 99.01% | Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor. | ||||||||||||||||||||
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Prunetin (Standard) | ≥98% | Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor. | ||||||||||||||||||||
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References
- [1]. Hu H, et al. Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells. Biomed Pharmacother. 2018 Oct;106:1469-1477. [Content Brief]
- [2]. Sheikh S, et al. Allosteric inhibition of human liver aldehyde dehydrogenase by the isoflavone prunetin. Biochem Pharmacol. 1997 Feb 21;53(4):471-8. [Content Brief]
Keywords
