552-59-0
552-59-0
Chemical Structure
Prunetin
- CAS No.: 552-59-0
- Formula:C16H12O5
- Molecular Weight:284.26
IUPAC Name: 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4H-chromen-4-one
InChIKey: KQMVAGISDHMXJJ-UHFFFAOYSA-N
SMILES: O=C1C(C2=CC=C(O)C=C2)=COC3=CC(OC)=CC(O)=C13
Biological Activity: Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Prunetin | 99.01% | Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor. | ||||||||||||||||||||
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Prunetin (Standard) | ≥98% | Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor. | ||||||||||||||||||||
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Genistein 7-sulfate | Genistein 7-sulfate is a metabolite of Genistein (HY-14596). Genistein 7-sulfate weakly induces PON1 transactivation. Genistein 7-sulfate induces ALP activity. Genistein 7-sulfate can be used in research on breast cancer and liver cancer. | |||||||||||||||||||||
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Biochanin A | 99.33% | Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor, which inhibits FAAH with IC50s of 1.8, 1.4 and 2.4 μM for mouse, rat, and human FAAH, respectively. | ||||||||||||||||||||
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Genistein (Standard) | 98.70% | Genistein (Standard) is the analytical standard of Genistein. This product is intended for research and analytical applications. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis. | ||||||||||||||||||||
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Glycitein (Standard) | ≥98% | Glycitein (Standard) is the analytical standard of Glycitein. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Tectorigenin | 99.89% | Tectorigenin is a plant isoflavonoid originally isolated from the dried flower of Pueraria lobate Benth. | ||||||||||||||||||||
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Cajanin | 99.96% | Cajanin is a potent and orally active anti-melanogenic agent. Cajanin shows antiproliferative activity in MNT1 Cells. Cajanin efficiently decreases the melanin content. Cajanin down-regulates the mRNA and protein expression levels of MITF, tyrosinase, TRP-1 and Dct (TRP-2). Cajanin induces cell cycle arrest at G2/M and S phase. Cajanin stimulates osteoblast proliferation. Cajanin has the potential for the research of human hyperpigmented disorders and menopausal osteoporosis. | ||||||||||||||||||||
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Isoformononetin | 99.47% | Isoformononetin is an analog of Daidzein (HY-N0019) and has immunoprotective effects. Isoformononetin inhibits the differentiation of Th17 and B-cells lymphopoesis to promote osteogenesis in estrogen-deficient bone loss conditions. | ||||||||||||||||||||
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7-O-Methylbiochanin A | 98.83% | 7-O-Methylbiochanin A (4',7-Dimethoxy-5-hydroxyisoflavone) is an isoflavone derivative isolated from the roots of Lotus polyphyllos. | ||||||||||||||||||||
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7,3'-Di-O-Methylorobol | 7,3'-Di-O-Methylorobol is a flavone that can be isolated from Sophora japonica. | |||||||||||||||||||||
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5-O-Methylgenistein | 99.03% | 5-O-Methylgenistein (Isoprunetin) is an isoflavone that can be isolated from M. amurensis wood. 5-O-Methylgenistein inhibits β-gal activityy induced by 17β-Estradiol (HY-B0141) in yeast. | ||||||||||||||||||||
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References
- [1]. Hu H, et al. Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells. Biomed Pharmacother. 2018 Oct;106:1469-1477. [Content Brief]
- [2]. Sheikh S, et al. Allosteric inhibition of human liver aldehyde dehydrogenase by the isoflavone prunetin. Biochem Pharmacol. 1997 Feb 21;53(4):471-8. [Content Brief]
