552325-16-3
552325-16-3
Chemical Structure
Rizavasertib
Synonym(s): A-443654
- CAS No.: 552325-16-3
- Formula:C24H23N5O
- Molecular Weight:397.47
IUPAC Name: (S)-1-(1H-indol-3-yl)-3-((5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl)oxy)propan-2-amine
InChIKey: YWTBGJGMTBHQTM-IBGZPJMESA-N
SMILES: N[C@H](COC1=CN=CC(C2=CC3=C(NN=C3C)C=C2)=C1)CC4=CNC5=CC=CC=C54
Biological Activity: A-443654 is a pan-Akt inhibitor and has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Rizavasertib | 99.04% | A-443654 is a pan-Akt inhibitor and has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM). | ||||||||||||||||||||
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Rizavasertib (Standard) | ≥98% | Rizavasertib (Standard) is the analytical standard of Rizavasertib (HY-10425). This product is intended for research and analytical applications. A-443654 is a pan-Akt inhibitor and has equal potency against Akt1, Akt2, or Akt3 within cells (Ki=160 pM). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.79
HY-13254AA-674563 hydrochloride -
Similarity Score 0.78
HY-13254A-674563 -
Similarity Score 0.66
HY-125201Indazole 1 -
Similarity Score 0.63
HY-123390DB07107 -
Similarity Score 0.61
HY-162398LQ23 -
Similarity Score 0.51
HY-118131PKR-IN-C51 -
Similarity Score 0.51
HY-47733CDK1/2/4-IN-2 -
Similarity Score 0.51
HY-138815(S)-N-(1H-Indole-3-acetyl)tryptophan -
Similarity Score 0.50
HY-153540AP-C4 -
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