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Art. -Nr.: HY-47733

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CDK1/2/4-IN-2

WAY-643018 (Compound 2), an indazolecarboxamide derivative, is a CDK1, CDK2, and CDK4 inhibitor. CDK1/2/4-IN-2 has the potential for cancer research.

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CAS. Nr.: 677701-62-1
Formel: C₁₈H₁₆N₄O
Molecular Weight:304.35

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

CDK1/2/4-IN-2 Chemical Structure

CAS. Nr.: 677701-62-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

WAY-643018 (Compound 2), an indazolecarboxamide derivative, is a CDK1, CDK2, and CDK4 inhibitor. CDK1/2/4-IN-2 has the potential for cancer research^[1].

Alle CDK Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
Erythrocyte	IC₅₀	>9.13 μg/mL Compound: TDR81382	WHO-TDR: Malaria WHO-TDR: Malaria	10.6019/CHEMBL2093137
Macrophage	IC₅₀	>9.13 μg/mL Compound: TDR81382	WHO-TDR: Leishmaniasis WHO-TDR: Leishmaniasis	10.6019/CHEMBL2093137
MRC5	IC₅₀	>9.13 μg/mL Compound: TDR81382	WHO-TDR: Cytotoxicity WHO-TDR: Cytotoxicity	10.6019/CHEMBL2093137
MRC5	IC₅₀	8.203 μg/mL Compound: TDR81382	WHO-TDR: Chagas disease WHO-TDR: Chagas disease	10.6019/CHEMBL2093137

Chemical Information

CAS. Nr. 677701-62-1
Molecular Weight 304.35
Formel C₁₈H₁₆N₄O
SMILES

O=C(C1=NNC2=C1C=CC=C2)NCCC3=CNC4=C3C=CC=C4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Orchymont HD, et, al. INDAZOLECARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THERAPEUTICS. FR2845382A1.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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