CDK1/2/4-IN-2
WAY-643018 (Compound 2), an indazolecarboxamide derivative, is a CDK1, CDK2, and CDK4 inhibitor. CDK1/2/4-IN-2 has the potential for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 677701-62-1
- Formula: C18H16N4O
- Molecular Weight:304.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Erythrocyte | IC50 |
>9.13 μg/mL
Compound: TDR81382
|
WHO-TDR: Malaria
WHO-TDR: Malaria
|
10.6019/CHEMBL2093137 |
| Macrophage | IC50 |
>9.13 μg/mL
Compound: TDR81382
|
WHO-TDR: Leishmaniasis
WHO-TDR: Leishmaniasis
|
10.6019/CHEMBL2093137 |
| MRC5 | IC50 |
>9.13 μg/mL
Compound: TDR81382
|
WHO-TDR: Cytotoxicity
WHO-TDR: Cytotoxicity
|
10.6019/CHEMBL2093137 |
| MRC5 | IC50 |
8.203 μg/mL
Compound: TDR81382
|
WHO-TDR: Chagas disease
WHO-TDR: Chagas disease
|
10.6019/CHEMBL2093137 |
Chemical Information
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CAS No. 677701-62-1
-
Molecular Weight 304.35
-
Formula C18H16N4O
-
SMILES
O=C(C1=NNC2=C1C=CC=C2)NCCC3=CNC4=C3C=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)