5560-72-5
5560-72-5
Chemical Structure
Iprindole
- CAS No.: 5560-72-5
- Formula:C19H28N2
- Molecular Weight:284.44
IUPAC Name: 3-(6,7,8,9,10,11-hexahydro-5H-cycloocta[b]indol-5-yl)-N,N-dimethylpropan-1-amine
InChIKey: PLIGPBGDXASWPX-UHFFFAOYSA-N
SMILES: CN(C)CCCN1C2=C(CCCCCC2)C3=C1C=CC=C3
Biological Activity: Iprindole, an opioid receptor agonist, is a tricyclic antidepressant. Iprindole shortens the immobility time in mice forced swimming test, which can be reversed by the opiate antagonist Naloxone (HY-17417A). Iprindole induces lamellar body formation but devoid of lamellar bodies. Iprindole can be used for the research of depression[1][2][3].
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Iprindole | 99.55% | Iprindole, an opioid receptor agonist, is a tricyclic antidepressant. Iprindole shortens the immobility time in mice forced swimming test, which can be reversed by the opiate antagonist Naloxone (HY-17417A). Iprindole induces lamellar body formation but devoid of lamellar bodies. Iprindole can be used for the research of depression. | ||||||||||||||||||||
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Iprindole (Standard) | ≥98% | Iprindole (Standard) is the analytical standard of Iprindole. This product is intended for research and analytical applications. Iprindole, an opioid receptor agonist, is a tricyclic antidepressant. Iprindole shortens the immobility time in mice forced swimming test, which can be reversed by the opiate antagonist Naloxone (HY-17417A). Iprindole induces lamellar body formation but devoid of lamellar bodies. Iprindole hydrochloride can be used for the research of depression. | ||||||||||||||||||||
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References
- [1]. Baxter BL, et al. Iprindole: an antidepressant which does not block REM sleep. Nature. 1969 Aug 16;223(5207):750-2. [Content Brief]
- [2]. de Felipe MC, et al. Antidepressant action of imipramine and iprindole in mice is enhanced by inhibitors of enkephalin-degrading peptidases. Eur J Pharmacol. 1989 Jan 10;159(2):175-80. [Content Brief]
- [3]. Martin WJ 2nd, et al. Iprindole reverses the lamellar body deficiency of cultured L-2 cells. Possible implications in the reversal of surfactant deficiency. Am J Pathol. 1987 Oct;129(1):34-43. [Content Brief]
