57-41-0
57-41-0
Chemical Structure
Phenytoin
Synonym(s): 5,5-Diphenylhydantoin
- CAS No.: 57-41-0
- Formula:C15H12N2O2
- Molecular Weight:252.27
IUPAC Name: 5,5-diphenylimidazolidine-2,4-dione
InChIKey: CXOFVDLJLONNDW-UHFFFAOYSA-N
SMILES: O=C1NC(C(C2=CC=CC=C2)(C3=CC=CC=C3)N1)=O
Biological Activity: Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice[1][2].
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Phenytoin | 99.95% | Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice. | ||||||||||||||||||||
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Phenytoin (Standard) | 99.94% | Phenytoin (Standard) is the analytical standard of Phenytoin. This product is intended for research and analytical applications. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice. | ||||||||||||||||||||
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Phenytoin-d5 | Phenytoin-d5 (5,5-Diphenylhydantoin-d5) is deuterium labeled Phenytoin. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice. | |||||||||||||||||||||
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Phenytoin-d10 | 99.50% | Phenytoin-d10 is the deuterium labeled Phenytoin. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice. | ||||||||||||||||||||
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Phenytoin-15N2,13C | 99.84% | Phenytoin-15N2,13C is the 13C and 15N labeled Phenytoin. Phenytoin (5,5-Diphenylhydantoin) is a potent Voltage-gated Na+ channels (VGSCs) blocker. Phenytoin has antiepileptic activity and reduces breast tumour growth and metastasis in mice. | ||||||||||||||||||||
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References
- [1]. Michaela Nelson, et al. The sodium channel-blocking antiepileptic drug phenytoin inhibits breast tumour growth and metastasis. Mol Cancer. 2015 Jan 27;14(1):13. [Content Brief]
- [2]. Rogawski, M.A. and W. Loscher, The neurobiology of antiepileptic drugs. Nat Rev Neurosci, 2004. 5(7): p. 553-64. [Content Brief]
