57460-41-0
57460-41-0
Chemical Structure
Talinolol
Synonym(s): Cordanum
- CAS No.: 57460-41-0
- Formula:C20H33N3O3
- Molecular Weight:363.49
IUPAC Name: 1-(4-(3-(tert-butylamino)-2-hydroxypropoxy)phenyl)-3-cyclohexylurea
InChIKey: MXFWWQICDIZSOA-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(OCC(O)CNC(C)(C)C)C=C1)NC2CCCCC2
Biological Activity: Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity[1][2].
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Talinolol | 99.56% | Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity. | ||||||||||||||||||||
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Talinolol (Standard) | ≥98% | Talinolol (Standard) is the analytical standard of Talinolol (HY-108286). This product is intended for research and analytical applications. Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity. | ||||||||||||||||||||
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(Rac)-Talinolol-d5 | (Rac)-Talinolol-d5 is the racemate of Talinolol. Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity. | |||||||||||||||||||||
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References
- [1]. Assmann I. The actions of talinolol, a beta 1-selective beta blocker, in cardiac arrhythmia and acute myocardial infarction. Curr Med Res Opin. 1995;13(6):325-42. [Content Brief]
- [2]. Kara ZP, et, al. The effects of P-glycoprotein inhibitor zosuquidar on the sex and time-dependent pharmacokinetics of parenterally administered talinolol in mice. Eur J Pharm Sci. 2021 Jan 1;156:105589. [Content Brief]
