1. GPCR/G Protein
  2. Adrenergic Receptor
  3. (+)-Penbutolol

(+)-Penbutolol (Synonyms: (R)-Penbutolol; (+)-Isopenbutolol)

Cat. No.: HY-116790A
Handling Instructions

(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action.

For research use only. We do not sell to patients.

(+)-Penbutolol Chemical Structure

(+)-Penbutolol Chemical Structure

CAS No. : 38363-41-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 165 In-stock
Estimated Time of Arrival: December 31
5 mg USD 150 In-stock
Estimated Time of Arrival: December 31
10 mg USD 240 In-stock
Estimated Time of Arrival: December 31
50 mg USD 750 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

(+)-Penbutolol is a β-adrenoceptor antagonist, with an IC50 of 0.74 μM[1]. (+)-Penbutolol is an optical isomer of l-penbutolol with Na+ channel-blocking action[2].

IC50 & Target

IC50: 0.74 μM (β-adrenoceptor)[1].

In Vitro

(+)-penbutolol on the [Ca2+]i-increase induced by LPC is concentration-dependent[1].
(+)-penbutolol inhibits the rounding of cells dose dependently (8±4%, 56±4% and 66±2% at the concentrations of 10-6 M, 5×10-6 M and 10-5 M, respectively)[2].

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References
Molecular Weight

291.43

Formula

C₁₈H₂₉NO₂

CAS No.

38363-41-6

SMILES

O[[email protected]@H](COC1=C(C=CC=C1)C2CCCC2)CNC(C)(C)C

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
(+)-Penbutolol
Cat. No.:
HY-116790A
Quantity:

(+)-Penbutolol

Cat. No.: HY-116790A