57564-91-7
57564-91-7
Chemical Structure
Nitrosoglutathione
Synonym(s): GSNO; RVC-588; S-Nitroso-L-glutathione
- CAS No.: 57564-91-7
- Formula:C10H16N4O7S
- Molecular Weight:336.32
IUPAC Name: N5-((R)-1-((carboxymethyl)amino)-3-(nitrosothio)-1-oxopropan-2-yl)-L-glutamine
InChIKey: HYHSBSXUHZOYLX-WDSKDSINSA-N
SMILES: OC(CNC([C@H](CSN=O)NC(CC[C@H](N)C(O)=O)=O)=O)=O
Biological Activity: Nitrosoglutathione (GSNO), a exogenous NO donor and a substrate for rat alcohol dehydrogenase class III isoenzyme, inhibits cerebrovascular angiotensin II-dependent and -independent AT1 receptor responses[1][2][3][4].
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Nitrosoglutathione | 90.0% | Nitrosoglutathione (GSNO), a exogenous NO donor and a substrate for rat alcohol dehydrogenase class III isoenzyme, inhibits cerebrovascular angiotensin II-dependent and -independent AT1 receptor responses. | ||||||||||||||||||||
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Nitrosoglutathione (Standard) | ≥98% | Nitrosoglutathione (Standard) (GSNO (Standard)) is the analytical standard of Nitrosoglutathione (HY-D0845). This product is intended for research and analytical applications. Nitrosoglutathione (GSNO), a exogenous NO donor and a substrate for rat alcohol dehydrogenase class III isoenzyme, inhibits cerebrovascular angiotensin II-dependent and -independent AT1 receptor responses. x | ||||||||||||||||||||
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References
- [1]. Marie-Lynda Bouressam, et al. S-nitrosoglutathione inhibits cerebrovascular angiotensin II-dependent and -independent AT 1 receptor responses: A possible role of S-nitrosation. Br J Pharmacol. 2019 Jun;176(12):2049-2062. [Content Brief]
- [2]. D E Jensen, et al. S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme. Biochem J. 1998 Apr 15;331 ( Pt 2)(Pt 2):659-68. [Content Brief]
- [3]. Caneta Brown, et al. The effects of S-nitrosoglutathione and S-nitroso-N-acetyl-D, L-penicillamine in a rat model of pre-eclampsia. J Nat Sci Biol Med. 2013 Jul;4(2):330-5. [Content Brief]
- [4]. Yur-Ren Kuo, et al. Nitrosoglutathione promotes flap survival via suppression of reperfusion injury-induced superoxide and inducible nitric oxide synthase induction. J Trauma. 2004 Nov;57(5):1025-31. [Content Brief]
