584-69-0
Chemical Structure
Ditophal
Synonym(s): Etisul
- CAS No.: 584-69-0
- Formula:C12H14O2S2
- Molecular Weight:254.36
IUPAC Name: S,S-diethyl benzene-1,3-bis(carbothioate)
InChIKey: DWGXUDUOJPYAOR-UHFFFAOYSA-N
SMILES: O=C(SCC)C1=CC=CC(=C1)C(=O)SCC
Biological Activity: Ditophal is an orally active thiol ester anti-tuberculosis and anti-leprosy agent. Ditophal combats Mycobacterium tuberculosis infections in subcutaneous and intracerebral sites in guinea pigs, including isoniazid (HY-B0329)-resistant strains. Ditophal alters the staining characteristics of Mycobacterium leprae and reduces the bacterial index of leprosy. Ditophal causes ulcers at the injection site when administered subcutaneously to guinea pigs at high doses. Ditophal can be used in the research of tuberculosis and leprosy[1][2].
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Ditophal | Ditophal is an orally active thiol ester anti-tuberculosis and anti-leprosy agent. Ditophal combats Mycobacterium tuberculosis infections in subcutaneous and intracerebral sites in guinea pigs, including isoniazid (HY-B0329)-resistant strains. Ditophal alters the staining characteristics of Mycobacterium leprae and reduces the bacterial index of leprosy. Ditophal causes ulcers at the injection site when administered subcutaneously to guinea pigs at high doses. Ditophal can be used in the research of tuberculosis and leprosy. | |||||||||||||||||||||
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Keywords
