59-96-1
59-96-1
Chemical Structure
Phenoxybenzamine
- CAS No.: 59-96-1
- Formula:C18H22ClNO
- Molecular Weight:303.83
IUPAC Name: N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine
InChIKey: QZVCTJOXCFMACW-UHFFFAOYSA-N
SMILES: CC(N(CCCl)CC1=CC=CC=C1)COC2=CC=CC=C2
Biological Activity: Phenoxybenzamine is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine also shows antitumor activity[1][2].
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Phenoxybenzamine | Phenoxybenzamine is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine also shows antitumor activity. | |||||||||||||||||||||
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Phenoxybenzamine-d5 | Phenoxybenzamine-d5 is the deuterium labeled Phenoxybenzamine. Phenoxybenzamine is a nonselective, irreversible, orally active α-adrenoceptor antagonist that is commonly used for the research of hypertension, specifically caused by pheochromocytoma. Phenoxybenzamine also shows antitumor activity. | |||||||||||||||||||||
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References
- [1]. Habbe N, et al. Urapidil in the preoperative treatment of pheochromocytomas: a safe and cost-effective method. World J Surg. 2013 May;37(5):1141-6. [Content Brief]
- [2]. Lin XB, et al. Anti-tumor activity of phenoxybenzamine hydrochloride on malignant glioma cells. Tumour Biol. 2016 Mar;37(3):2901-8. [Content Brief]
