5908-62-3
Chemical Structure
1,3-Propanesultam
Synonym(s): 1,1-Dioxoisothiazolidine
- CAS No.: 5908-62-3
- Formula:C3H7NO2S
- Molecular Weight:121.16
IUPAC Name: isothiazolidine 1,1-dioxide
InChIKey: XGYCWCIGCYGQFU-UHFFFAOYSA-N
SMILES: O=S1(NCCC1)=O
Biological Activity: 1,3-Propanesultam (1,1-Dioxoisothiazolidine) is a cyclic sulfonamide monomer. Polymerization of 1,3-Propanesultam under base catalysis produces high-molecular-weight polypropanesulfonamide, while polymerization under acid catalysis yields low-molecular-weight polypropanesulfonamide. 1,3-Propanesultam serves as a coupling partner in copper-catalyzed C-N cross-coupling reactions for the synthesis of 3-aminopyrazole phenylacetamide analogs. 1,3-Propanesultam is applicable to research related to organic synthesis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1,3-Propanesultam | 98.50% | 1,3-Propanesultam (1,1-Dioxoisothiazolidine) is a cyclic sulfonamide monomer. Polymerization of 1,3-Propanesultam under base catalysis produces high-molecular-weight polypropanesulfonamide, while polymerization under acid catalysis yields low-molecular-weight polypropanesulfonamide. 1,3-Propanesultam serves as a coupling partner in copper-catalyzed C-N cross-coupling reactions for the synthesis of 3-aminopyrazole phenylacetamide analogs. 1,3-Propanesultam is applicable to research related to organic synthesis. | ||||||||||||||||||||
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References
- [1]. Welton-Arndt A, et al. Toward a Small Molecule Therapy for Angelman Syndrome: Structure-Activity Relationship Studies of 3-Aminopyrazole Phenylacetamides as Paternal Unsilencers. Journal of medicinal chemistry. 2026 May 28;69(10):12260-12290. [Content Brief]
- [2]. Bliss, A. D.,et al. Synthesis and Polymerization of Propanesultam. Journal of Organic Chemistry, 1963, 28(12): 3537-3541.
