593273-05-3
593273-05-3
Chemical Structure
DCH36_06
- CAS No.: 593273-05-3
- Formula:C18H13ClN2O3S
- Molecular Weight:372.83
IUPAC Name: (E)-1-(3-chloro-4-methylphenyl)-5-((E)-3-(furan-2-yl)allylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
InChIKey: AYNCXNUUERDREH-FMDPHQNASA-N
SMILES: O=C(/C(C(N1C2=CC=C(C)C(Cl)=C2)=O)=C\C=C\C3=CC=CO3)NC1=S
Biological Activity: DCH36_06 is a potent and selective p300/CBP inhibitor with IC50s of 0.6 μM and 3.2 μM for p300 and CBP, respectively. DCH36_06 mediated p300/CBP inhibition leading to hypoacetylation on H3K18 in leukemic cells. Anti-tumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DCH36_06 | 99.19% | DCH36_06 is a potent and selective p300/CBP inhibitor with IC50s of 0.6 μM and 3.2 μM for p300 and CBP, respectively. DCH36_06 mediated p300/CBP inhibition leading to hypoacetylation on H3K18 in leukemic cells. Anti-tumor activity. | ||||||||||||||||||||
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References
Keywords
