593273-05-3

DCH36_06 Chemical Structure
593273-05-3

Chemical Structure

DCH36_06

  • CAS. Nr.: 593273-05-3
  • Formula:C18H13ClN2O3S
  • Molecular Weight:372.83

IUPAC Name: (E)-1-(3-chloro-4-methylphenyl)-5-((E)-3-(furan-2-yl)allylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

InChIKey: AYNCXNUUERDREH-FMDPHQNASA-N

SMILES: O=C(/C(C(N1C2=CC=C(C)C(Cl)=C2)=O)=C\C=C\C3=CC=CO3)NC1=S

Biological Activity: DCH36_06 is a potent and selective p300/CBP inhibitor with IC50s of 0.6 μM and 3.2 μM for p300 and CBP, respectively. DCH36_06 mediated p300/CBP inhibition leading to hypoacetylation on H3K18 in leukemic cells. Anti-tumor activity[1].

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-139108 		DCH36_06 99.19% DCH36_06 is a potent and selective p300/CBP inhibitor with IC50s of 0.6 μM and 3.2 μM for p300 and CBP, respectively. DCH36_06 mediated p300/CBP inhibition leading to hypoacetylation on H3K18 in leukemic cells. Anti-tumor activity.
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This product is a controlled substance and not for sale in your territory.

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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

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Keywords