61389-26-2
61389-26-2
Chemical Structure
Lignoceric acid-d4
Synonym(s): Tetracosanoic acid-d4
- CAS. Nr.: 61389-26-2
- Formula:C24H44D4O2
- Molecular Weight:372.66
IUPAC Name: tetracosanoic-3,3,5,5-d4 acid
InChIKey: QZZGJDVWLFXDLK-CMJIWFEKSA-N
SMILES: CCCCCCCCCCCCCCCCCCCC([2H])([2H])CC([2H])([2H])CC(O)=O
Biological Activity: Lignoceric acid-d4 (Tetracosanoic acid-d4) is deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2][1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Lignoceric acid-d4 | Lignoceric acid-d4 (Tetracosanoic acid-d4) is deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research. | |||||||||||||||||||||
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Lignoceric acid (Standard) | ≥98% | Lignoceric acid (Standard) is the analytical standard of Lignoceric acid. This product is intended for research and analytical applications. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research. | ||||||||||||||||||||
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Lignoceric acid-d4-2 | 98.7% | Lignoceric acid-d4-2 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research. | ||||||||||||||||||||
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Lignoceric acid-d3 | 99.00% | Lignoceric acid-d3 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research. | ||||||||||||||||||||
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Lignoceric acid-d47 | 99.91% | Lignoceric acid-d47 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research. | ||||||||||||||||||||
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Lignoceric acid-d9 | 98.0% | Lignoceric acid-d9 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research. | ||||||||||||||||||||
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Lignoceric acid-d4-1 | 98.80% | Lignoceric acid-d4-11 is the deuterium labeled Lignoceric acid. Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research. | ||||||||||||||||||||
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Lignoceric acid | 98.61% | Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research. | ||||||||||||||||||||
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Hexacosanoic acid | 98.15% | Hexacosanoic acid is a very long-chain fatty acid. Abnormally elevated levels of Hexacosanoic acid are closely associated with various diseases, such as X-linked adrenoleukodystrophy, adrenomyeloneuropathy, atherosclerosis, and dementia. | ||||||||||||||||||||
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Hexacosanoic acid-d4-1 | 98.0% | Hexacosanoic acid-d4-11 is the deuterium labeled Hexacosanoic acid (HY-113301). Hexacosanoic acid is a very long-chain fatty acid. Abnormally elevated levels of Hexacosanoic acid are closely associated with various diseases, such as X-linked adrenoleukodystrophy, adrenomyeloneuropathy, atherosclerosis, and dementia. | ||||||||||||||||||||
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Heneicosanoic acid (Standard) | ≥98% | Heneicosanoic acid (Standard) is the analytical standard of Heneicosanoic acid. This product is intended for research and analytical applications. Heneicosanoic acid is a long-chain saturated fatty acid which is found in plants and animals. | ||||||||||||||||||||
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Pentacosanoic acid | 99.57% | Pentacosanoic acid is a 25-carbon long-chain saturated fatty acid. Pentacosanoic is a conjugate acid of a pentacosanoate. | ||||||||||||||||||||
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24-Methylpentacosanoic acid | 24-Methylpentacosanoic acid is an ester product. | |||||||||||||||||||||
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Palmitic acid-d4 | 99.88% | Palmitic acid-d4 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. | ||||||||||||||||||||
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Pentacosane-d52 | 98.59% | Pentacosane-d52 is the deuterium labeled Pentacosane. Pentacosane is one of the major components in the acetone extract from Curcuma raktakanda and is also in the essential oil from the leaves of Malus domestica. Pentacosane exhibit anti-cancer activities. | ||||||||||||||||||||
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Tetracosane-d50 | 99.0% | Tetracosane-d50 is the deuterium labeled Tetracosane. | ||||||||||||||||||||
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Octacosanoic acid (Standard) | ≥98% | Octacosanoic acid (Montanic acid) (Standard) is the analytical standard of Octacosanoic acid (Montanic acid) (HY-N8425). This product is intended for research and analytical applications. Octacosanoic acid (Montanic acid) is a long-chain saturated fatty acid and a major component of sugarcane wax mixture and D-003. Octacosanoic acid can be formed in the liver from Octacosanol (HY-N6811) and inhibits nitric oxide (NO) production in LPS-activated macrophages and LPS-induced splenic lymphocyte proliferation. Octacosanoic acid can be used in anti-inflammatory and lipid metabolism-related research. | ||||||||||||||||||||
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Docosane-d46 | Docosane-d46 is the deuterated-labeled Docosane (HY-N9929). Docosane is a plant resistance inducer found in Frullania probosciphora. Docosane induces activation of the salicylic acid signaling pathway. Docosane induces activation of the jasmonic acid signaling pathway. Docosane induces activation of the ethylene signaling pathway. Docosane can be used in research on tomato bacterial wilt and apple fire blight. | |||||||||||||||||||||
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Arachidic acid-d39 | 99.95% | Arachidic acid-d39 is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research. | ||||||||||||||||||||
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Arachidic acid-d4 | 99.20% | Arachidic acid-d4 is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research. | ||||||||||||||||||||
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Arachidic acid-d4-1 | Arachidic acid-d4-1 is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research. | |||||||||||||||||||||
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Nonadecanoic acid-d37 | 99.30% | Nonadecanoic acid-d37 is the deuterium labeled Nonadecanoic acid. Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis to defence. | ||||||||||||||||||||
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Heptadecanoic acid-d33 | 99.88% | Heptadecanoic acid-d33 is the deuterium labeled Heptadecanoic acid. Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis. | ||||||||||||||||||||
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Methyl arachidate-d39 | Methyl arachidate-d39 is the deuterated Methyl arachidate. Methyl arachidate, a natural compound, is a?leukotriene A4 hydrolase?(LTA4H)?inhibitor | |||||||||||||||||||||
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Tricosanoic acid | 99.96% | Tricosanoic acid is an endogenous agonist of long-chain saturated fatty acids and free fatty acid receptor FFAR1, which can activate hair growth. Tricosanoic acid (C23:0) has the activity of improving cognitive function by regulating neuronal membrane fluidity, inhibiting neuroinflammatory response, participating in myelination and neuronal energy metabolism. Tricosanoic acid expression levels are low in the prefrontal cortex of Alzheimer's disease (AD) models; while better cognitive performance corresponds to higher serum concentration levels. Tricosanoic acid can be used as a biomarker for diseases related to cognitive decline. | ||||||||||||||||||||
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Docosanoic acid | 99.40% | Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans. | ||||||||||||||||||||
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Docosanoic acid-d43 | 99.91% | Docosanoic acid-d43 (Behenic acid-d43) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans. | ||||||||||||||||||||
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Docosanoic acid-d4-1 | 99.85% | Docosanoic acid-d4-1 (Behenic acid-d4-1) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans. | ||||||||||||||||||||
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Docosanoic acid-d4-2 | 99.94% | Docosanoic acid-d4-2 (Behenic acid-d4-2) is the deuterium labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in humans. | ||||||||||||||||||||
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Docosanoic acid-13C4 | Docosanoic acid-13C4 (Behenic acid-13C4) is the 13C-labeled Docosanoic acid (HY-W013049). Docosanoic acid (Behenic acid) is a long-chain saturated fatty acid. Docosanoic acid inhibits the double-stranded DNA (dsDNA) binding activity of p53 DNA binding domain, with a Kd of 12 nM. Docosanoic acid has low bioavailability and can increase cholesterol in vivo. | |||||||||||||||||||||
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Heptacosanoic acid (Standard) | ≥98% | Heptacosanoic acid (Standard) is the analytical standard of Heptacosanoic acid (HY-W127566). This product is intended for research and analytical applications. Heptacosanoic Acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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Tricosane-d48 | Tricosane-d48 is the deuterium labeled Tricosane. | |||||||||||||||||||||
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Behenate sodium | 99.85% | Behenate (sodium) is an ester product. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Anna Petroni, et al. Thermogenic flux induced by lignoceric acid in peroxisomes isolated from HepG2 cells and from X-adrenoleukodystrophy and control fibroblasts. J Cell Physiol. 2019 Aug;234(10):18344-18348. [Content Brief]
- [3]. J M Bourre, et al. Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy). Eur J Biochem. 1977 Jan 3;72(1):41-7. [Content Brief]
