2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Lignoceric acid

Lignoceric acid  (Synonyms: Tetracosanoic acid)

Cat. No.: HY-121883 Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research.

For research use only. We do not sell to patients.

Lignoceric acid Chemical Structure

Lignoceric acid Chemical Structure

CAS No. : 557-59-5

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100 mg USD 80 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Lignoceric acid:

Lignoceric acid Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro‐hepato‐renal syndrome and adrenoleukodystrophy research[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Heat flux induced by lignoceric acid in HepG2 peroxisomes was exothermic, indicating normal peroxisomal metabolism[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lignoceric acid Related Antibodies
Molecular Weight

368.64

Formula

C24H48O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCCCCCCCCCCCCCCCCCC(O)=O
Structure Classification
Initial Source

Bee Pollen
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

THF : 25 mg/mL (67.82 mM; Need ultrasonic)

Ethanol : 8.33 mg/mL (22.60 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7127 mL 13.5634 mL 27.1267 mL
5 mM 0.5425 mL 2.7127 mL 5.4253 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% EtOH    90% Corn Oil

    Solubility: ≥ 0.83 mg/mL (2.25 mM); Clear solution

    This protocol yields a clear solution of ≥ 0.83 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

    Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (8.3 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (237 KB) HNMR (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / THF 1 mM 2.7127 mL 13.5634 mL 27.1267 mL 67.8168 mL
5 mM 0.5425 mL 2.7127 mL 5.4253 mL 13.5634 mL
10 mM 0.2713 mL 1.3563 mL 2.7127 mL 6.7817 mL
15 mM 0.1808 mL 0.9042 mL 1.8084 mL 4.5211 mL
20 mM 0.1356 mL 0.6782 mL 1.3563 mL 3.3908 mL
THF 25 mM 0.1085 mL 0.5425 mL 1.0851 mL 2.7127 mL
30 mM 0.0904 mL 0.4521 mL 0.9042 mL 2.2606 mL
40 mM 0.0678 mL 0.3391 mL 0.6782 mL 1.6954 mL
50 mM 0.0543 mL 0.2713 mL 0.5425 mL 1.3563 mL
60 mM 0.0452 mL 0.2261 mL 0.4521 mL 1.1303 mL
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Lignoceric acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lignoceric acid557-59-5Tetracosanoic acidEndogenous MetaboliteperoxisomalneurodegenerativefattyacidligninInhibitorinhibitorinhibit

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