64005-90-9
64005-90-9
Chemical Structure
PPIase-Parvulin inhibitor
- CAS No.: 64005-90-9
- Formula:C22H18N2O8
- Molecular Weight:438.39
IUPAC Name: diethyl 2,2'-(1,3,6,8-tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl)diacetate
InChIKey: WNKQGFNIIHNGQM-UHFFFAOYSA-N
SMILES: O=C(N(CC(OCC)=O)C1=O)C2=CC=C(C3=C4C=CC1=C23)C(N(CC(OCC)=O)C4=O)=O
Biological Activity: PPIase-Parvulin inhibitor (compound B) is a cell-permeable inhibitor targeting PPIase Pin1 and Par14, with IC50s of 1.5 and 1.0 µM, respectively. PPIase-Parvulin inhibitor has anticancer activity and inhibits the growth and proliferation of mouse embryonic fibroblasts (MEFs)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PPIase-Parvulin inhibitor | 98.09% | PPIase-Parvulin inhibitor (compound B) is a cell-permeable inhibitor targeting PPIase Pin1 and Par14, with IC50s of 1.5 and 1.0 µM, respectively. PPIase-Parvulin inhibitor has anticancer activity and inhibits the growth and proliferation of mouse embryonic fibroblasts (MEFs). | ||||||||||||||||||||
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M-31850 | 99.79% | M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor with IC50s of 6.0 μM and 3.1 μM for human HexA and human HexB, respectively. M-31850 also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM. | ||||||||||||||||||||
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MMV009085 | 98.68% | MMV009085 is a potent PfHT1 (Plasmodium falciparum hexose transporter)-specific inhibitor and a potential anti-malarial agent . MMV009085 is also a human glucose transporter inhibitor, it has high potency in inhibiting both glucose uptake (IC50: 2.6 μM in glucose uptake assay) and growth of the parasites (EC50: 1.23±0.04 μM against 3D7). | ||||||||||||||||||||
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Alrestatin | 99.21% | Alrestatin (AY-22284) is an aldose reductase inhibitor. Alrestatin reduces fructose levels in the uterine fluid of mice. Alrestatin interferes with sperm capacitation and impairs fertilization function in mice. Alrestatin decreases basal and tyramine-induced norepinephrine release in rat pancreatic specimens in vitro. Alrestatin enhances glucose- and arginine-stimulated insulin secretion in vivo. Alrestatin can be used in studies related to diabetes and reproductive diseases. | ||||||||||||||||||||
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Alrestatin sodium | Alrestatin (AY-22284) sodium is an aldose reductase inhibitor. Alrestatin sodium reduces fructose levels in the uterine fluid of mice. Alrestatin sodium interferes with sperm capacitation and impairs fertilization function in mice. Alrestatin sodium decreases basal and tyramine-induced norepinephrine release in rat pancreatic specimens in vitro. Alrestatin sodium enhances glucose- and arginine-stimulated insulin secretion in vivo. Alrestatin sodium can be used in studies related to diabetes and reproductive diseases. | |||||||||||||||||||||
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(2S,2'S)-2,2'-(1,3,8,10-Tetraoxo-1,3,8,10-tetrahydroanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-2,9-diyl)dipropionic acid | (2S,2'S)-2,2'-(1,3,8,10-Tetraoxo-1,3,8,10-tetrahydroanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-2,9-diyl)dipropionic acid (N, N'-bis (L-alanine) perylene diamide) is a metal-organic framework (MOF). | |||||||||||||||||||||
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1,3,6,8-Tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-dicarboxylic acid | 1,3,6,8-Tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-dicarboxylic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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2,7-Bis(pyridin-4-ylmethyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone | 2,7-Bis(pyridin-4-ylmethyl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone is a metal-organic framework (MOF). | |||||||||||||||||||||
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N,N′-Dipentyl-3,4,9,10-perylenedicarboximide | N,N′-Dipentyl-3,4,9,10-perylenedicarboximide (PTCDI-C5) is an organic semiconductor compound with excellent electron transport activity. N,N′-Dipentyl-3,4,9,10-perylenedicarboximide exhibits high performance in organic field effect transistors (OFETs) and can effectively improve the carrier mobility of the device. The application of N,N′-Dipentyl-3,4,9,10-perylenedicarboximide in organic photovoltaic (OPV) materials enhances the light absorption performance, thereby improving the photoelectric conversion efficiency. N,N′-Dipentyl-3,4,9,10-perylenedicarboximide has also been widely studied for the development of high-performance sensors and fluorescent materials. | |||||||||||||||||||||
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(2S,2'S)-2,2'-(1,3,6,8-Tetraoxobenzo[lmn][3,8]phenanthroline-2,7(1H,3H,6H,8H)-diyl)dipropanoic acid | (2S,2'S)-2,2'-(1,3,6,8-Tetraoxobenzo[lmn][3,8]phenanthroline-2,7(1H,3H,6H,8H)-diyl)dipropanoic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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2,2'-(1,3,6,8-Tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl)diacetic acid | 2,2'-(1,3,6,8-Tetraoxo-1,3,6,8-tetrahydrobenzo[lmn][3,8]phenanthroline-2,7-diyl)diacetic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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