648449-76-7
648449-76-7
Chemical Structure
AS-604850
- CAS No.: 648449-76-7
- Formula:C11H5F2NO4S
- Molecular Weight:285.22
IUPAC Name: (E)-5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methylene)thiazolidine-2,4-dione
InChIKey: SRLVNYDXMUGOFI-XBXARRHUSA-N
SMILES: O=C(NC/1=O)SC1=C\C2=CC=C(OC(F)(F)O3)C3=C2
Biological Activity: AS-604850 is a potent, selective and ATP-competitive PI3Kγ inhibitor with an IC50 value of 0.25 μM and a Ki value of 0.18 μM. AS-604850 shows isoform selective inhibitor of PI3Kγ with over 30-fold selectivity for PI3Kδ and β, and 18-fold selectivity over PI3Kα, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AS-604850 | 99.32% | AS-604850 is a potent, selective and ATP-competitive PI3Kγ inhibitor with an IC50 value of 0.25 μM and a Ki value of 0.18 μM. AS-604850 shows isoform selective inhibitor of PI3Kγ with over 30-fold selectivity for PI3Kδ and β, and 18-fold selectivity over PI3Kα, respectively. | ||||||||||||||||||||
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Structural Analogs
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