6920-35-0
Chemical Structure
(±)-Hexanoylcarnitine chloride
Synonym(s): DL-Hexanoylcarnitine chloride
- CAS No.: 6920-35-0
- Formula:C13H26ClNO4
- Molecular Weight:295.80
IUPAC Name: 3-carboxy-2-(hexanoyloxy)-N,N,N-trimethylpropan-1-aminium chloride
InChIKey: DTHGTKVOSRYXOK-UHFFFAOYSA-N
SMILES: CCCCCC(OC(CC(O)=O)C[N+](C)(C)C)=O.[Cl-]
Biological Activity: (±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±)-Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin (HY-129458) and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(±)-Hexanoylcarnitine chloride | 98.0% | (±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±)-Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin (HY-129458) and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways. | ||||||||||||||||||||
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References
- [1]. Scarale MG, et al. Circulating Metabolites Associate With and Improve the Prediction of All-Cause Mortality in Type 2 Diabetes. Diabetes. 2022 Jun 1;71(6):1363-1370. [Content Brief]
- [2]. Obayashi H, et al. Plasma 2-hydroxyglutarate and hexanoylcarnitine levels are potential biomarkers for skeletal muscle toxicity in male Fischer 344 rats. J Toxicol Sci. 2017;42(4):385-396. [Content Brief]
