(±)-Hexanoylcarnitine chloride
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(±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±)-Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin (HY-129458) and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 6920-35-0
- Formula: C13H26ClNO4
- Molecular Weight:295.80
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Endogenous Metabolite Isoforms
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Biological Activity
Chemical Information
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CAS No. 6920-35-0
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Appearance Solid
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Molecular Weight 295.80
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Formula C13H26ClNO4
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Color White to off-white
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SMILES
CCCCCC(OC(CC(O)=O)C[N+](C)(C)C)=O.[Cl-]
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Synonyms
DL-Hexanoylcarnitine chloride
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 250 mg/mL (845.17 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Scarale MG, et al. Circulating Metabolites Associate With and Improve the Prediction of All-Cause Mortality in Type 2 Diabetes. Diabetes. 2022 Jun 1;71(6):1363-1370. [Content Brief]
[2]. Obayashi H, et al. Plasma 2-hydroxyglutarate and hexanoylcarnitine levels are potential biomarkers for skeletal muscle toxicity in male Fischer 344 rats. J Toxicol Sci. 2017;42(4):385-396. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.3807 mL | 16.9033 mL | 33.8066 mL | 84.5166 mL |
| 5 mM | 0.6761 mL | 3.3807 mL | 6.7613 mL | 16.9033 mL | |
| 10 mM | 0.3381 mL | 1.6903 mL | 3.3807 mL | 8.4517 mL | |
| 15 mM | 0.2254 mL | 1.1269 mL | 2.2538 mL | 5.6344 mL | |
| 20 mM | 0.1690 mL | 0.8452 mL | 1.6903 mL | 4.2258 mL | |
| 25 mM | 0.1352 mL | 0.6761 mL | 1.3523 mL | 3.3807 mL | |
| 30 mM | 0.1127 mL | 0.5634 mL | 1.1269 mL | 2.8172 mL | |
| 40 mM | 0.0845 mL | 0.4226 mL | 0.8452 mL | 2.1129 mL | |
| 50 mM | 0.0676 mL | 0.3381 mL | 0.6761 mL | 1.6903 mL | |
| 60 mM | 0.0563 mL | 0.2817 mL | 0.5634 mL | 1.4086 mL | |
| 80 mM | 0.0423 mL | 0.2113 mL | 0.4226 mL | 1.0565 mL | |
| 100 mM | 0.0338 mL | 0.1690 mL | 0.3381 mL | 0.8452 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.