69955-43-7
Chemical Structure
DL-α-(Difluoromethyl)arginine
Synonym(s): RMI 71897
- CAS No.: 69955-43-7
- Formula:C7H14F2N4O2
- Molecular Weight:224.21
IUPAC Name: 2-amino-2-(difluoromethyl)-5-guanidinopentanoic acid
InChIKey: YEORLXJBCPPSOC-UHFFFAOYSA-N
SMILES: NC(CCCNC(N)=N)(C(F)F)C(O)=O
Biological Activity: DL-α-(Difluoromethyl)arginine (RMI 71897) is an enzyme-activated inhibitor of arginine decarboxylase. DL-α-(Difluoromethyl)arginine exhibits a Ki of 800 μM for the biosynthetic arginine decarboxylase of Escherichia coli and a Ki of 140 μM for the biodegradative arginine decarboxylase of Escherichia coli. DL-α-(Difluoromethyl)arginine selectively inhibits arginine decarboxylase activity in intact E. coli and Pseudomonas aeruginosa, indicating that it can be transported into bacteria. DL-α-(Difluoromethyl)arginine can be used in metabolism-related research[1].
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DL-α-(Difluoromethyl)arginine | 95% | DL-α-(Difluoromethyl)arginine (RMI 71897) is an enzyme-activated inhibitor of arginine decarboxylase. DL-α-(Difluoromethyl)arginine exhibits a Ki of 800 μM for the biosynthetic arginine decarboxylase of Escherichia coli and a Ki of 140 μM for the biodegradative arginine decarboxylase of Escherichia coli. DL-α-(Difluoromethyl)arginine selectively inhibits arginine decarboxylase activity in intact E. coli and Pseudomonas aeruginosa, indicating that it can be transported into bacteria. DL-α-(Difluoromethyl)arginine can be used in metabolism-related research. | ||||||||||||||||||||
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