700874-72-2
700874-72-2
Chemical Structure
Galunisertib
Synonym(s): LY2157299
- CAS No.: 700874-72-2
- Formula:C22H19N5O
- Molecular Weight:369.42
IUPAC Name: 4-(2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide
InChIKey: IVRXNBXKWIJUQB-UHFFFAOYSA-N
SMILES: CC1=CC=CC(C2=NN3C(CCC3)=C2C4=CC=NC5=C4C=C(C=C5)C(N)=O)=N1
Biological Activity: Galunisertib (LY2157299) is an oral and selective TGF-β receptor type I (TGF-βRI) kinase inhibitor with an IC50 of 56 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Galunisertib | 99.90% | Galunisertib (LY2157299) is an oral and selective TGF-β receptor type I (TGF-βRI) kinase inhibitor with an IC50 of 56 nM. | ||||||||||||||||||||
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Galunisertib (Standard) | 98.95% | Galunisertib (Standard) is the analytical standard of Galunisertib. This product is intended for research and analytical applications. Galunisertib (LY2157299) is an oral and selective TGF-β receptor type I (TGF-βRI) kinase inhibitor with an IC50 of 56 nM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-13226AGalunisertib monohydrate -
Similarity Score 0.84
HY-160237HYL001 -
Similarity Score 0.70
HY-W028145TGF-βRI inhibitor 2 -
Similarity Score 0.70
HY-W684904LY550410 -
Similarity Score 0.65
HY-182547LY580276 -
Similarity Score 0.65
HY-160215GFH018 -
Similarity Score 0.62
HY-12075RLY2109761 (Standard) -
Similarity Score 0.57
HY-160215AGFH018 methylbenzenesulfonate -
Similarity Score 0.55
HY-10432RA 83-01 (Standard) -
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