7029-89-2
7029-89-2
Chemical Structure
DPBQ
- CAS No.: 7029-89-2
- Formula:C24H14N2O2
- Molecular Weight:362.38
IUPAC Name: 2,3-diphenylbenzo[g]quinoxaline-5,10-dione
InChIKey: BDDRJIAFKGWLMD-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CC=C12)C3=C(N=C(C4=CC=CC=C4)C(C5=CC=CC=C5)=N3)C2=O
Biological Activity: DPBQ activates p53 and triggers apoptosis in a polyploid-specific manner, but does not inhibit topoisomerase or bind DNA. DPBQ elicits expression and phosphorylation of p53 and this effect is specific to tetraploid cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DPBQ | 99.46% | DPBQ activates p53 and triggers apoptosis in a polyploid-specific manner, but does not inhibit topoisomerase or bind DNA. DPBQ elicits expression and phosphorylation of p53 and this effect is specific to tetraploid cells. | ||||||||||||||||||||
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I-XW-053 | 99.71% | I-XW-053 is a specific anti-HIV-1 capsid inhibitor (IC50=164.2 μM). By binding to the CA NTD-NTD hexamerization interface and the R173 region of CTD (Kd=66.3 μM), I-XW-053 disrupts capsid function and reduces polymerization levels. I-XW-053 effectively blocks HIV-1 uncoating, inhibits reverse transcription and early replication, and exhibits broad-spectrum activity against primary HIV-1 isolates in peripheral blood mononuclear cells. I-XW-053 can be widely used in studies related to HIV-1 infection. | ||||||||||||||||||||
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I-XW-053 sodium | I-XW-053 sodium is a specific anti-HIV-1 capsid inhibitor (IC50=164.2 μM). By binding to the CA NTD-NTD hexamerization interface and the R173 region of CTD (Kd=66.3 μM), I-XW-053 sodium disrupts capsid function and reduces polymerization levels. I-XW-053 sodium effectively blocks HIV-1 uncoating, inhibits reverse transcription and early replication, and exhibits broad-spectrum activity against primary HIV-1 isolates in peripheral blood mononuclear cells. I-XW-053 sodium can be widely used in studies related to HIV-1 infection. | |||||||||||||||||||||
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AKT-IN-20 | AKT-IN-20 is an AKT inhibitor, and can be used for research of cancer | |||||||||||||||||||||
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5-Chloro-2,3-diphenylpyrazine (Standard) | ≥98% | 5-Chloro-2,3-diphenylpyrazine (Standard) is the analytical standard of 5-Chloro-2,3-diphenylpyrazine. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Bathocuproine | 98.01% | Bathocuproine is a phenanthroline chelator that binds specifically to Cu+. Bathocuproine preferentially binds Cu+ over Cu2+ to form a chromogenic complex, which is used to detect the oxidation state of copper in biomolecules. Bathocuproine undergoes concentration-dependent self-association to form dimers, and it can engage in aromatic stacking interactions with aromatic residues of Aβ (Kd ≈ 1 mM). Bathocuproine is applicable to research related to Alzheimer's disease. | ||||||||||||||||||||
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4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride | 98.0% | 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride (DIB-Cl) is a fluorescent labeling reagent. 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzoyl chloride can be used for labeling amines and successfully being applied to determine activator amines by HPLC. | ||||||||||||||||||||
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4-(4,5-Diphenyl-1H-imidazol-2-yl)phenol | 4-(4,5-Diphenyl-1H-imidazol-2-yl)phenol is an organic compound commonly used in fluorescent dyes and catalysts. It can be used to prepare some organic light-emitting diodes (OLEDs) and organic solar cells, and is widely used in chemical sensors and analytical instruments. In addition, this compound is used as a catalyst or buffer in certain chemical reactions. | |||||||||||||||||||||
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Lophine | 99.03% | Lophine is a traditional chemiluminescent and fluorescent probe. Lophine and its derivatives are widely applied for reactive oxygen species (ROS) detection. | ||||||||||||||||||||
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2,3-Diphenylquinoxaline-6-carboxylic acid | 99.95% | 2,3-Diphenylquinoxaline-6-carboxylic acid is used for end-capping in the synthesis of AB2 monomers, which facilitates the synthesis and chain-end modification of hyperbranched polymers containing alternating quinoxaline and benzoxazole repeating units. | ||||||||||||||||||||
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4-(4,5-Diphenyl-1H-imidazol-2-yl)pyridine | 4-(4,5-Diphenyl-1H-imidazol-2-yl)pyridine is a metal-organic framework (MOF). | |||||||||||||||||||||
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