708-06-5
708-06-5
Chemical Structure
CFL-137
- CAS No.: 708-06-5
- Formula:C11H8O2
- Molecular Weight:172.18
IUPAC Name: 2-Hydroxy-1-naphthaldehyde
InChIKey: NTCCNERMXRIPTR-UHFFFAOYSA-N
SMILES: O=CC1=C2C=CC=CC2=CC=C1O
Biological Activity: CFL-137 is a potent KRasG12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CFL-137 | 99.92% | CFL-137 is a potent KRasG12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer. | ||||||||||||||||||||
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CFL-137 (Standard) | ≥98% | CFL-137 is a potent KRasG12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer. | ||||||||||||||||||||
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1,2-Dihydroxynaphthalene | 98.88% | 1,2-Dihydroxynaphthalene (1,2-Naphthalenediol) is a metabolic intermediate of Naphthalene and a precursor for the formation of 1,2-Naphthoquinone, and is also the most sensitive biomarker of Naphthalene exposure in humans. 1,2-Dihydroxynaphthalene inhibits the AMPK/SIRT3 pathway and activates acetylated p53 and NF-κB by inducing oxidative stress, leading to G2/M cell cycle arrest, senescence, and apoptosis, while also damaging DNA through the formation of depurination adducts, thereby causing mutations. 1,2-Dihydroxynaphthalene can be used in research on cancer and cataracts. | ||||||||||||||||||||
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Naphthalene-1,2-dicarbaldehyde | Naphthalene-1,2-dicarbaldehyde is a fluorescent dye. | |||||||||||||||||||||
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1-Hydroxy-2-naphthoic acid | 99.78% | 1-Hydroxy-2-naphthoic acid is a ubiquitous bicyclic intermediate metabolite in the microbial degradation process of polycyclic aromatic hydrocarbons (PAHs). 1-Hydroxy-2-naphthoic acid can be converted into 1,2-naphthalenediol, which enters the naphthalene degradation pathway and participates in the tricarboxylic acid (TCA) cycle to achieve complete mineralization. | ||||||||||||||||||||
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2'-Hydroxy-1'-acetonaphthone | 99.69% | 2'-Hydroxy-1'-acetonaphthone is a Schiff base used as pharmaceutical intermediates. | ||||||||||||||||||||
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2-Acetyl-1-naphthol | 2-Acetyl-1-naphthol (compound 32) is a naphthol derivative with no HDAC inhibitor activity. | |||||||||||||||||||||
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Naphthohydroquinone | Naphthohydroquinone is a compound featuring a naphthalene ring structure with two hydroxyl groups. Naphthohydroquinone exhibits significant cytotoxicity and antitumor activity in some of its derivatives. | |||||||||||||||||||||
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2-Naphthaldehyde | 99.80% | 2-Naphthaldehyde belongs to naphthalene-based bis-aromatic aldehyde compounds. 2-Naphthaldehyde scavenges DPPH and ABTS+ free radicals, and exerts reductive effects by donating hydrogen atoms to interrupt free radical chain reactions. 2-Naphthaldehyde inhibits the growth and proliferation of colon cancer cells. 2-Naphthaldehyde serves as a substrate for NAD+-dependent salicylaldehyde dehydrogenase from Pseudomonas strain C6 and is catalytically oxidized. 2-Naphthaldehyde acts as a precursor material for the chemical synthesis of antioxidant Schiff bases. | ||||||||||||||||||||
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2-Naphthaldehyde-13C | 2-Naphthaldehyde-13C is the 13C-labeled 2-Naphthaldehyde (HY-Y0075). 2-Naphthaldehyde belongs to naphthalene-based bis-aromatic aldehyde compounds. 2-Naphthaldehyde scavenges DPPH and ABTS+ free radicals, and exerts reductive effects by donating hydrogen atoms to interrupt free radical chain reactions. 2-Naphthaldehyde inhibits the growth and proliferation of colon cancer cells. 2-Naphthaldehyde serves as a substrate for NAD+-dependent salicylaldehyde dehydrogenase from Pseudomonas strain C6 and is catalytically oxidized. 2-Naphthaldehyde acts as a precursor material for the chemical synthesis of antioxidant Schiff bases. | |||||||||||||||||||||
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1,5-Dihydroxynaphthalene (Standard) | ≥98% | 1,5-Dihydroxynaphthalene (Standard) is the analytical standard of 1,5-Dihydroxynaphthalene. This product is intended for research and analytical applications. | ||||||||||||||||||||
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1-Naphthol | 99.90% | 1-naphthol (Furro ER) is an excited state proton transfer (ESPT) fluorescent molecular probe. 1-naphthol can sense the hydrophobic domains in micellar aggregation and accurately sense the sol-gel transition. 1-naphthol can be used to study the thermally induced microenvironmental changes and hydration levels of Pluronic F127 (PF127) in different microenvironments in aqueous media. | ||||||||||||||||||||
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