7203-91-0
7203-91-0
Chemical Structure
CB10-277
- CAS No.: 7203-91-0
- Formula:C9H11N3O2
- Molecular Weight:193.20
IUPAC Name: (E)-4-(3,3-dimethyltriaz-1-en-1-yl)benzoic acid
InChIKey: GUAZPUYTLMUTMA-ZHACJKMWSA-N
SMILES: O=C(C1=CC=C(C=C1)/N=N/N(C)C)O
Biological Activity: CB10-277 is a Dacarbazine (HY-B0078) analog that mediates alkylation of guanine residues at the O6 position in DNA and subsequently reduces ATase levels in lymphocytes and tumors. CB10-277 is useful in the study of metastatic malignant melanoma[1].
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CB10-277 | CB10-277 is a Dacarbazine (HY-B0078) analog that mediates alkylation of guanine residues at the O6 position in DNA and subsequently reduces ATase levels in lymphocytes and tumors. CB10-277 is useful in the study of metastatic malignant melanoma. | |||||||||||||||||||||
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