7380-40-7
7380-40-7
Chemical Structure
Bergamottin
Synonym(s): 5-Geranoxypsoralen; Bergamotine; Bergaptin
- CAS No.: 7380-40-7
- Formula:C21H22O4
- Molecular Weight:338.40
IUPAC Name: (E)-4-((3,7-dimethylocta-2,6-dien-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one
InChIKey: DBMJZOMNXBSRED-OQLLNIDSSA-N
SMILES: O=C1C=CC2=C(OC/C=C(C)/CC/C=C(C)/C)C3=C(OC=C3)C=C2O1
Biological Activity: Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM.
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Bergamottin | 99.94% | Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM. | ||||||||||||||||||||
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Bergamottin (Standard) | ≥98% | Bergamottin (Standard) is the analytical standard of Bergamottin. This product is intended for research and analytical applications. Bergamottin is a potent and competitive CYP1A1 inhibitor with a Ki of 10.703 nM. | ||||||||||||||||||||
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6',7'-Epoxybergamottin | 98.7% | 6',7'-Epoxybergamottin is a metabolism of Penicillium digitatum. 6',7'-Epoxybergamottin can be used in study the cytochrome P450 3A4 inhibitory activity. | ||||||||||||||||||||
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O-Methylnotoptol | O‑Methylnotoptol is a Coumarin (HY-N0709) isolated from the roots and rhizomes of Notopterygium incisum. O‑Methylnotoptol inhibits LPS‑induced nitric oxide production in RAW 264.7 murine macrophages with an IC50 value of 23.9 μM. | |||||||||||||||||||||
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O-Methylnotopterol | O-Methylnotopterol is a coumarin compound. O-Methylnotopterol inhibits LPS (HY-D1056)-induced nitric oxide production with an IC50 value of 12.7 μM. | |||||||||||||||||||||
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Isoimperatorin | 99.78% | Isoimperatorin is a methanolic extract of the roots of Angelica dahurica shows significant inhibitory effects on acetylcholinesterase (AChE) with the IC50 of 74.6 μM. | ||||||||||||||||||||
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Notopterol (Standard) | ≥98% | Notopterol (Standard) is the analytical standard of Notopterol. This product is intended for research and analytical applications. Notopterol is a coumarin extracted from N. incisum. Notopterol induces apoptosis and has antipyretic, analgesic and anti-inflammatory effects. Notopterol is used for acute myeloid leukemia (AML). | ||||||||||||||||||||
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Notoptol | Notoptol can be isolated from the fruit of Peucedanum alsaticum L. | |||||||||||||||||||||
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Ethylnotopterol | Ethylnotopterol is a coumarin found in the roots and rhizomes of Notopterygium incisum and an inhibitor with an IC50 value of 18.1 μM for LPS-induced nitric oxide production. Ethylnotopterol blocks LPS-induced nitric oxide production in macrophage cells. | |||||||||||||||||||||
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(R)-6',7'-Dihydroxybergamottin | (R)-6',7'-Dihydroxybergamottin ((R)-6′,7′-DHB) is a competitive inhibitor of human and rat CYP1A1 activity with Kis of 55 μM and 1.72 μM, respectively. (R)-6',7'-Dihydroxybergamottin has the potential for cancer research. | |||||||||||||||||||||
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6',7'-Dihydroxybergamottin | 99.0% | 6',7'-Dihydroxybergamottin (6′,7′-DHB), a furanocoumarin, is a potent CYP3A4 inhibitor. | ||||||||||||||||||||
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Anhydronotoptol | Anhydronotoptol is a potent nitric oxide inhibitory coumarin. Anhydronotoptol inhibits NO production in RAW 264.7 cells induced by LPS with an IC50 value of 36.6 μM. | |||||||||||||||||||||
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