744-59-2
744-59-2
Chemical Structure
Hippuryl-L-phenylalanine
- CAS No.: 744-59-2
- Formula:C18H18N2O4
- Molecular Weight:326.35
IUPAC Name: benzoylglycyl-L-phenylalanine
InChIKey: CCLJGZGVIQBNDH-HNNXBMFYSA-N
SMILES: O=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(C2=CC=CC=C2)=O)=O
Biological Activity: Hippuryl-L-phenylalanine is a substrate of carboxypeptidase. Carboxypeptidase is a protease enzyme that related with obesity, epilepsy and neurodegeneration. Hippuryl-L-phenylalanine can be used for the determination of carboxypeptidase activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Hippuryl-L-phenylalanine | 98.65% | Hippuryl-L-phenylalanine is a substrate of carboxypeptidase. Carboxypeptidase is a protease enzyme that related with obesity, epilepsy and neurodegeneration. Hippuryl-L-phenylalanine can be used for the determination of carboxypeptidase activity. | ||||||||||||||||||||
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Phelorphan | Phelorphan is a purine MTH1 inhibitor identified through chemical array screening. Although it targets cellular MTH1, its cytotoxicity to cancer cells is weaker than that of other reported inhibitors. The cytotoxicity of MTH1 inhibitors may be attributed to off-target effects, and MTH1 is not essential for cancer cell survival. | |||||||||||||||||||||
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Benzoyl-L-phenylalanine | 99.68% | Benzoyl-L-phenylalanine (N-Benzoyl-L-phenylalanine) is a chorisate mutase-prephenate dehydrogenase inhibitor. | ||||||||||||||||||||
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N-(Phenylacetyl)-L-phenylalanine | 98.43% | N-(Phenylacetyl)-L-phenylalanine (N-Phenylacetylphenylalanine) is an amino acid analog. N-(Phenylacetyl)-L-phenylalanine is produced via the enantioselective acylation of L-phenylalanine catalyzed by penicillin G acylase from Alcaligenes faecalis. N-(Phenylacetyl)-L-phenylalanine undergoes hydrolysis in aqueous media. | ||||||||||||||||||||
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N-Phenethylbenzamide | 99.89% | N-Phenethylbenzamide is an active compound. N-Phenethylbenzamide can be extracted from Liriodendron tulipifera. N-Phenethylbenzamide can be used for the research of inflammatory diseases. | ||||||||||||||||||||
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Ac-Phe-Phe-OH | Ac-Phe-Phe-OH is a negatively charged analogue of the diphenylalanine peptide that forms large aggregates when combined with the NH2-Phe-Phe-OH peptide. | |||||||||||||||||||||
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H-Phe-Phe-OH | 99.66% | H-Phe-Phe-OH is a peptide made of two phenylalanine molecules; Phenylalanine is an essential amino acid and the precursor for the amino acid tyrosine. | ||||||||||||||||||||
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((Benzyloxy)carbonyl)-D-phenylalanine | 99.25% | ((Benzyloxy)carbonyl)-D-phenylalanine is a phenylalanine derivative. | ||||||||||||||||||||
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Z-Phe-OH | 99.48% | Z-Phe-OH is a phenylalanine derivative. | ||||||||||||||||||||
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H-Gly-Gly-Phe-OH | 99.89% | H-Gly-Gly-Phe-OH is a tripeptide linker that may be used in the creation of antibody drug conjugates (ADCs). The N-terminal of the glycine tripeptide is free to perform a variety of reactions such as couplings with carboxylic acids or NHS esters. | ||||||||||||||||||||
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Z-Gly-Gly-Phe-OH | 99.46% | Z-Gly-Gly-Phe-OH is a substrate for pepsin and thermolysin. Z-Gly-Gly-Phe-OH has an IC50 of 15.8 μM for open sodium channels under pepsin catalysis. Z-Gly-Gly-Phe-OH forms peptide bonds with amine components (such as H-Leu-NHPh) through enzyme-catalyzed condensation reactions, and is active as an intermediate in peptide synthesis. | ||||||||||||||||||||
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References
- [1]. Serafin WE, et al. Carboxypeptidase A in mouse mast cells. Identification, characterization, and use as a differentiation marker. J Immunol. 1987 Dec 1;139(11):3771-6. [Content Brief]
- [2]. Sapio MR, Fricker LD. Carboxypeptidases in disease: insights from peptidomic studies. Proteomics Clin Appl. 2014 Jun;8(5-6):327-37.
